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A vitamin-C-derived DNA modification catalysed by an algal TET homologue.
Xue JH, Chen GD, Hao F, Chen H, Fang Z, Chen FF, Pang B, Yang QL, Wei X, Fan QQ, Xin C, Zhao J, Deng X, Wang BA, Zhang XJ, Chu Y, Tang H, Yin H, Ma W, Chen L, Ding J, Weinhold E, Kohli RM, Liu W, Zhu ZJ, Huang K, Tang H, Xu GL. Xue JH, et al. Nature. 2019 May;569(7757):581-585. doi: 10.1038/s41586-019-1160-0. Epub 2019 May 1. Nature. 2019. PMID: 31043749 Free PMC article.
RNA Pol II as a sensor of 5caC.
Xue JH, Xu GL. Xue JH, et al. Cell Res. 2015 Oct;25(10):1089-90. doi: 10.1038/cr.2015.103. Epub 2015 Aug 28. Cell Res. 2015. PMID: 26315484 Free PMC article.
Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation.
Xue JH, Xu GF, Gu TP, Chen GD, Han BB, Xu ZM, Bjørås M, Krokan HE, Xu GL, Du YR. Xue JH, et al. J Biol Chem. 2016 Jan 8;291(2):731-8. doi: 10.1074/jbc.M115.693861. Epub 2015 Nov 30. J Biol Chem. 2016. PMID: 26620559 Free PMC article.
The strand-biased mitochondrial DNA methylome and its regulation by DNMT3A.
Dou X, Boyd-Kirkup JD, McDermott J, Zhang X, Li F, Rong B, Zhang R, Miao B, Chen P, Cheng H, Xue J, Bennett D, Wong J, Lan F, Han JJ. Dou X, et al. Genome Res. 2019 Oct;29(10):1622-1634. doi: 10.1101/gr.234021.117. Epub 2019 Sep 19. Genome Res. 2019. PMID: 31537639 Free PMC article.
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis.
Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen CW, Huang W, Horne D, Rosen ST, He C, Chen J. Su R, et al. Nat Cell Biol. 2022 Feb;24(2):205-216. doi: 10.1038/s41556-021-00835-2. Epub 2022 Feb 10. Nat Cell Biol. 2022. PMID: 35145225 Free PMC article.
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia.
Chen Z, Zhou K, Xue J, Small A, Xiao G, Nguyen LXT, Zhang Z, Prince E, Weng H, Huang H, Zhao Z, Qing Y, Shen C, Li W, Han L, Tan B, Su R, Qin H, Li Y, Wu D, Gu Z, Ngo VN, He X, Chao J, Leung K, Wang K, Dong L, Qin X, Cai Z, Sheng Y, Chen Y, Wu X, Zhang B, Shi Y, Marcucci G, Qian Z, Xu M, Müschen M, Chen J, Deng X. Chen Z, et al. Sci Transl Med. 2023 Mar 29;15(689):eabq8513. doi: 10.1126/scitranslmed.abq8513. Epub 2023 Mar 29. Sci Transl Med. 2023. PMID: 36989375
162 results