Xu Z - Search Results

1

Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease.

Moll M, Boueiz A, Ghosh AJ, Saferali A, Lee S, Xu Z, Yun JH, Hobbs BD, Hersh CP, Sin DD, Tal-Singer R, Silverman EK, Cho MH, Castaldi PJ; HAPIN Investigators. Moll M, et al. Among authors: xu z. Am J Respir Crit Care Med. 2022 Jan 15;205(2):161-170. doi: 10.1164/rccm.202107-1584OC. Am J Respir Crit Care Med. 2022. PMID: 34739356 Free PMC article.

2

Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

Ghosh AJ, Hobbs BD, Yun JH, Saferali A, Moll M, Xu Z, Chase RP, Morrow J, Ziniti J, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner G, Brown KK, Wise R, Martinez FJ, McGoldrick D, Cho MH, DeMeo DL, Silverman EK, Castaldi PJ; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Hersh CP. Ghosh AJ, et al. Among authors: xu z. Respir Res. 2022 Apr 21;23(1):97. doi: 10.1186/s12931-022-02013-w. Respir Res. 2022. PMID: 35449067 Free PMC article.

3

Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.

Wang Z, Masoomi A, Xu Z, Boueiz A, Lee S, Zhao T, Bowler R, Cho M, Silverman EK, Hersh C, Dy J, Castaldi PJ. Wang Z, et al. Among authors: xu z. PLoS Comput Biol. 2021 Oct 11;17(10):e1009433. doi: 10.1371/journal.pcbi.1009433. eCollection 2021 Oct. PLoS Comput Biol. 2021. PMID: 34634029 Free PMC article.

4

Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease.

Lackey L, Coria A, Ghosh AJ, Grayeski P, Hatfield A, Shankar V, Platig J, Xu Z, Ramos SBV, Silverman EK, Ortega VE, Cho MH, Hersh CP, Hobbs BD, Castaldi P, Laederach A. Lackey L, et al. Among authors: xu z. PLoS Genet. 2021 Nov 16;17(11):e1009912. doi: 10.1371/journal.pgen.1009912. eCollection 2021 Nov. PLoS Genet. 2021. PMID: 34784346 Free PMC article.

5

An interferon-inducible signature of airway disease from blood gene expression profiling.

Yun JH, Lee S, Srinivasa P, Morrow J, Chase R, Saferali A, Xu Z, Cho M, Castaldi P, Hersh CP. Yun JH, et al. Among authors: xu z. Eur Respir J. 2022 May 19;59(5):2100569. doi: 10.1183/13993003.00569-2021. Print 2022 May. Eur Respir J. 2022. PMID: 34649980 Free PMC article.

6

Machine Learning Prediction of Progression in Forced Expiratory Volume in 1 Second in the COPDGene® Study.

Boueiz A, Xu Z, Chang Y, Masoomi A, Gregory A, Lutz SM, Qiao D, Crapo JD, Dy JG, Silverman EK, Castaldi PJ; COPDGene Investigators. Boueiz A, et al. Among authors: xu z. Chronic Obstr Pulm Dis. 2022 Jul 29;9(3):349-365. doi: 10.15326/jcopdf.2021.0275. Chronic Obstr Pulm Dis. 2022. PMID: 35649102 Free PMC article.

7

Clustering-based COPD subtypes have distinct longitudinal outcomes and multi-omics biomarkers.

Gregory A, Xu Z, Pratte K, Lee S, Liu C, Chase R, Yun J, Saferali A, Hersh CP, Bowler R, Silverman E, Castaldi PJ, Boueiz A. Gregory A, et al. Among authors: xu z. BMJ Open Respir Res. 2022 Aug;9(1):e001182. doi: 10.1136/bmjresp-2021-001182. BMJ Open Respir Res. 2022. PMID: 35999035 Free PMC article.

8

Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation.

Xu Z, Platig J, Lee S, Boueiz A, Chase R, Jain D, Gregory A, Suryadevara R, Berman S, Bowler R, Hersh CP, Laederach A, Castaldi PJ; COPDGene Investigators. Xu Z, et al. Genomics. 2021 Nov;113(6):4184-4195. doi: 10.1016/j.ygeno.2021.11.004. Epub 2021 Nov 8. Genomics. 2021. PMID: 34763026 Free PMC article.

9

Characterization of a COPD-Associated NPNT Functional Splicing Genetic Variant in Human Lung Tissue via Long-Read Sequencing.

Saferali A, Xu Z, Sheynkman GM, Hersh CP, Cho MH, Silverman EK, Laederach A, Vollmers C, Castaldi PJ. Saferali A, et al. Among authors: xu z. medRxiv [Preprint]. 2020 Nov 3:2020.10.20.20203927. doi: 10.1101/2020.10.20.20203927. medRxiv. 2020. PMID: 33173926 Free PMC article. Preprint.

10

Targeted expression profiling by RNA-Seq improves detection of cellular dynamics during pregnancy and identifies a role for T cells in term parturition.

Tarca AL, Romero R, Xu Z, Gomez-Lopez N, Erez O, Hsu CD, Hassan SS, Carey VJ. Tarca AL, et al. Among authors: xu z. Sci Rep. 2019 Jan 29;9(1):848. doi: 10.1038/s41598-018-36649-w. Sci Rep. 2019. PMID: 30696862 Free PMC article.

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