Xu YH - Search Results

1

Palladium oxidative addition complex-enabled synthesis of amino-substituted indolyl-4(3H)-quinazolinones and their antitumor activity evaluation.

Jiang Z, Zhao DD, Hu YT, Rao Y, Guo SY, Xu YH, Li Q, Huang ZS. Jiang Z, et al. Among authors: xu yh. Org Biomol Chem. 2022 Jan 19;20(3):553-557. doi: 10.1039/d1ob02307a. Org Biomol Chem. 2022. PMID: 34932056

2

New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC Transcription.

Liu HY, Chen AC, Yin QK, Li Z, Huang SM, Du G, He JH, Zan LP, Wang SK, Xu YH, Tan JH, Ou TM, Li D, Gu LQ, Huang ZS. Liu HY, et al. Among authors: xu yh. J Med Chem. 2017 Jul 13;60(13):5438-5454. doi: 10.1021/acs.jmedchem.7b00099. Epub 2017 Jun 28. J Med Chem. 2017. PMID: 28603988

3

Design, synthesis and biological evaluation of novel bouchardatine analogs as potential inhibitors of adipogenesis/lipogenesis in 3T3-L1 adipocytes.

Gao L, Xu Z, Rao Y, Lu YT, Hu YT, Yu H, Xu YH, Song QQ, Ye JM, Huang ZS. Gao L, et al. Among authors: xu yh, xu z. Eur J Med Chem. 2018 Mar 10;147:90-101. doi: 10.1016/j.ejmech.2018.01.089. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29425817

4

Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis.

Xu YH, Song QQ, Li C, Hu YT, Song BB, Ye JM, Rao Y, Huang ZS. Xu YH, et al. Eur J Pharmacol. 2019 Jul 5;854:328-337. doi: 10.1016/j.ejphar.2019.04.029. Epub 2019 Apr 24. Eur J Pharmacol. 2019. PMID: 31028741

5

Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity.

Rao Y, Lu YT, Li C, Song QQ, Xu YH, Xu Z, Hu YT, Yu H, Gao L, Gu LQ, Ye JM, Huang ZS. Rao Y, et al. Among authors: xu yh, xu z. Br J Pharmacol. 2019 Aug;176(16):2877-2893. doi: 10.1111/bph.14713. Epub 2019 Jul 4. Br J Pharmacol. 2019. PMID: 31113010 Free PMC article.

6

Pyridocarbazole alkaloids from Ochrosia borbonica: lipid-lowering agents inhibit the cell proliferation and adipogenesis of 3T3-L1 adipocyte via intercalating into supercoiled DNA.

Xu YH, Li W, Rao Y, Huang ZS, Yin S. Xu YH, et al. Chin J Nat Med. 2019 Sep;17(9):663-671. doi: 10.1016/S1875-5364(19)30080-9. Chin J Nat Med. 2019. PMID: 31526501

7

Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders.

Rao Y, Xu Z, Hu YT, Li C, Xu YH, Song QQ, Yu H, Song BB, Chen SB, Li QJ, Huang SL, Tan JH, Ou TM, Wang HG, Zhong GP, Ye JM, Huang ZS. Rao Y, et al. Among authors: xu yh, xu z. Eur J Med Chem. 2020 Apr 15;192:112172. doi: 10.1016/j.ejmech.2020.112172. Epub 2020 Feb 27. Eur J Med Chem. 2020. PMID: 32163815

8

Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors.

Wang CX, Zhang ZL, Yin QK, Tu JL, Wang JE, Xu YH, Rao Y, Ou TM, Huang SL, Li D, Wang HG, Li QJ, Tan JH, Chen SB, Huang ZS. Wang CX, et al. Among authors: xu yh. J Med Chem. 2020 Sep 10;63(17):9752-9772. doi: 10.1021/acs.jmedchem.0c00917. Epub 2020 Aug 7. J Med Chem. 2020. PMID: 32697083

9

Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis.

Rao Y, Kuang Z, Li C, Guo S, Xu Y, Zhao D, Hu Y, Song B, Jiang Z, Ge Z, Liu X, Li C, Chen S, Ye J, Huang Z, Lu Y. Rao Y, et al. Gut Microbes. 2021 Jan-Dec;13(1):1-19. doi: 10.1080/19490976.2021.1927633. Gut Microbes. 2021. PMID: 34030573 Free PMC article.

10

A novel HSF1 activator ameliorates non-alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation.

Rao Y, Li C, Hu YT, Xu YH, Song BB, Guo SY, Jiang Z, Zhao DD, Chen SB, Tan JH, Huang SL, Li QJ, Wang XJ, Zhang YJ, Ye JM, Huang ZS. Rao Y, et al. Among authors: xu yh. Br J Pharmacol. 2022 Apr;179(7):1411-1432. doi: 10.1111/bph.15727. Epub 2022 Feb 9. Br J Pharmacol. 2022. PMID: 34783017 Free article.

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