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A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.
Yu X, Ma H, Li B, Ji Y, Du Y, Liu S, Li Z, Hao Y, Tian S, Zhao C, Du Q, Jin Z, Zhu X, Tian Y, Chen X, Sun X, Yang C, Zhu F, Ju J, Zheng Y, Zhang W, Wang J, Yang T, Wang X, Li J, Xu X, Du S, Lu H, Ma F, Zhang H, Zhang Y, Zhang X, Hu S, He S. Yu X, et al. Among authors: xu x. Blood. 2023 Mar 2;141(9):1070-1086. doi: 10.1182/blood.2022017262. Blood. 2023. PMID: 36356302 Free PMC article.
Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas.
Kong S, Yang Y, Xu Y, Wang Y, Zhang Y, Melo-Cardenas J, Xu X, Gao B, Thorp EB, Zhang DD, Zhang B, Song J, Zhang K, Zhang J, Zhang J, Li H, Fang D. Kong S, et al. Among authors: xu x, xu y. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10394-9. doi: 10.1073/pnas.1606742113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573825 Free PMC article.
A multicenter, randomized, open-label, phase 2 clinical study of telitacicept in adult patients with generalized myasthenia gravis.
Yin J, Zhao M, Xu X, Zhang M, Xu Z, Li Z, Qin X, Li Z, Zhao C, Zhou H, Ma Y, Cao W, Wang G, Lin Y, Zhang J, Zhang X, Cai H, Qian W, Wang Y, Zhang X, Liu G, Wang J, Qiu W, Min L, Li J, Deng H, Chu L, Zhang Y, Fang J. Yin J, et al. Among authors: xu x. Eur J Neurol. 2024 May 10:e16322. doi: 10.1111/ene.16322. Online ahead of print. Eur J Neurol. 2024. PMID: 38726639
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