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In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis.
Padilha EC, Yang M, Shah P, Wang AQ, Duan J, Park JK, Zawatsky CN, Malicdan MCV, Kunos G, Iyer MR, Gaucher G, Ravenelle F, Cinar R, Xu X. Padilha EC, et al. Among authors: xu x. Biomed Pharmacother. 2023 Dec;168:115178. doi: 10.1016/j.biopha.2023.115178. Epub 2023 Oct 25. Biomed Pharmacother. 2023. PMID: 37890204 Free PMC article.
Preclinical validation of a novel therapeutic strategy for choroid plexus carcinoma.
Martin B, Garman T, Laramee M, Wang A, Zhang X, Beck E, Wilson K, Klumpp-Thomas C, McKnight C, Xu X, Hagen N, Holland D, Dahmane N, Thomas CJ, Souweidane M. Martin B, et al. Among authors: xu x. J Control Release. 2023 May;357:580-590. doi: 10.1016/j.jconrel.2023.04.016. Epub 2023 Apr 23. J Control Release. 2023. PMID: 37054779 Free PMC article.
Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products.
Yasgar A, Bougie D, Eastman RT, Huang R, Itkin M, Kouznetsova J, Lynch C, McKnight C, Miller M, Ngan DK, Peryea T, Shah P, Shinn P, Xia M, Xu X, Zakharov AV, Simeonov A. Yasgar A, et al. Among authors: xu x. ACS Pharmacol Transl Sci. 2023 Apr 14;6(5):683-701. doi: 10.1021/acsptsci.2c00194. eCollection 2023 May 12. ACS Pharmacol Transl Sci. 2023. PMID: 37200814 Free PMC article.
Artificial Intelligence in ADME Property Prediction.
Siramshetty VB, Xu X, Shah P. Siramshetty VB, et al. Among authors: xu x. Methods Mol Biol. 2024;2714:307-327. doi: 10.1007/978-1-0716-3441-7_17. Methods Mol Biol. 2024. PMID: 37676606
Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice.
Chandía-Cristi A, Gutiérrez DA, Dulcey AE, Lara M, Vargas L, Lin YH, Jimenez-Muñoz P, Larenas G, Xu X, Wang A, Owens A, Dextras C, Chen Y, Pinto C, Marín T, Almarza-Salazar H, Acevedo K, Cancino GI, Hu X, Rojas P, Ferrer M, Southall N, Henderson MJ, Zanlungo S, Marugan JJ, Álvarez R A. Chandía-Cristi A, et al. Among authors: xu x. Cell Rep. 2024 Apr 23;43(5):114144. doi: 10.1016/j.celrep.2024.114144. Online ahead of print. Cell Rep. 2024. PMID: 38656874 Free article.
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