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The Y chromosome: a blueprint for men's health?
Maan AA, Eales J, Akbarov A, Rowland J, Xu X, Jobling MA, Charchar FJ, Tomaszewski M. Maan AA, et al. Among authors: xu x. Eur J Hum Genet. 2017 Nov;25(11):1181-1188. doi: 10.1038/ejhg.2017.128. Epub 2017 Aug 30. Eur J Hum Genet. 2017. PMID: 28853720 Free PMC article. Review.
Molecular insights into genome-wide association studies of chronic kidney disease-defining traits.
Xu X, Eales JM, Akbarov A, Guo H, Becker L, Talavera D, Ashraf F, Nawaz J, Pramanik S, Bowes J, Jiang X, Dormer J, Denniff M, Antczak A, Szulinska M, Wise I, Prestes PR, Glyda M, Bogdanski P, Zukowska-Szczechowska E, Berzuini C, Woolf AS, Samani NJ, Charchar FJ, Tomaszewski M. Xu X, et al. Nat Commun. 2018 Nov 22;9(1):4800. doi: 10.1038/s41467-018-07260-4. Nat Commun. 2018. PMID: 30467309 Free PMC article.
Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
Rowland J, Akbarov A, Eales J, Xu X, Dormer JP, Guo H, Denniff M, Jiang X, Ranjzad P, Nazgiewicz A, Prestes PR, Antczak A, Szulinska M, Wise IA, Zukowska-Szczechowska E, Bogdanski P, Woolf AS, Samani NJ, Charchar FJ, Tomaszewski M. Rowland J, et al. Among authors: xu x. Kidney Int. 2019 Mar;95(3):624-635. doi: 10.1016/j.kint.2018.10.029. Kidney Int. 2019. PMID: 30784661 Free PMC article.
Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis.
Eales JM, Maan AA, Xu X, Michoel T, Hallast P, Batini C, Zadik D, Prestes PR, Molina E, Denniff M, Schroeder J, Bjorkegren JLM, Thompson J, Maffia P, Guzik TJ, Keavney B, Jobling MA, Samani NJ, Charchar FJ, Tomaszewski M. Eales JM, et al. Among authors: xu x. Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2386-2401. doi: 10.1161/ATVBAHA.119.312405. Epub 2019 Sep 5. Arterioscler Thromb Vasc Biol. 2019. PMID: 31644355 Free PMC article.
White Blood Cells and Blood Pressure: A Mendelian Randomization Study.
Siedlinski M, Jozefczuk E, Xu X, Teumer A, Evangelou E, Schnabel RB, Welsh P, Maffia P, Erdmann J, Tomaszewski M, Caulfield MJ, Sattar N, Holmes MV, Guzik TJ. Siedlinski M, et al. Among authors: xu x. Circulation. 2020 Apr 21;141(16):1307-1317. doi: 10.1161/CIRCULATIONAHA.119.045102. Epub 2020 Mar 9. Circulation. 2020. PMID: 32148083 Free PMC article. Clinical Trial.
Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney.
Jiang X, Eales JM, Scannali D, Nazgiewicz A, Prestes P, Maier M, Denniff M, Xu X, Saluja S, Cano-Gamez E, Wystrychowski W, Szulinska M, Antczak A, Byars S, Skrypnik D, Glyda M, Król R, Zywiec J, Zukowska-Szczechowska E, Burrell LM, Woolf AS, Greenstein A, Bogdanski P, Keavney B, Morris AP, Heagerty A, Williams B, Harrap SB, Trynka G, Samani NJ, Guzik TJ, Charchar FJ, Tomaszewski M. Jiang X, et al. Among authors: xu x. Eur Heart J. 2020 Dec 21;41(48):4580-4588. doi: 10.1093/eurheartj/ehaa794. Eur Heart J. 2020. PMID: 33206176 Free PMC article.
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
Breeze CE, Batorsky A, Lee MK, Szeto MD, Xu X, McCartney DL, Jiang R, Patki A, Kramer HJ, Eales JM, Raffield L, Lange L, Lange E, Durda P, Liu Y, Tracy RP, Van Den Berg D; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group; Evans KL, Kraus WE, Shah S, Tiwari HK, Hou L, Whitsel EA, Jiang X, Charchar FJ, Baccarelli AA, Rich SS, Morris AP, Irvin MR, Arnett DK, Hauser ER, Rotter JI, Correa A, Hayward C, Horvath S, Marioni RE, Tomaszewski M, Beck S, Berndt SI, London SJ, Mychaleckyj JC, Franceschini N. Breeze CE, et al. Among authors: xu x. Genome Med. 2021 Apr 30;13(1):74. doi: 10.1186/s13073-021-00877-z. Genome Med. 2021. PMID: 33931109 Free PMC article.
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.
Eales JM, Jiang X, Xu X, Saluja S, Akbarov A, Cano-Gamez E, McNulty MT, Finan C, Guo H, Wystrychowski W, Szulinska M, Thomas HB, Pramanik S, Chopade S, Prestes PR, Wise I, Evangelou E, Salehi M, Shakanti Y, Ekholm M, Denniff M, Nazgiewicz A, Eichinger F, Godfrey B, Antczak A, Glyda M, Król R, Eyre S, Brown J, Berzuini C, Bowes J, Caulfield M, Zukowska-Szczechowska E, Zywiec J, Bogdanski P, Kretzler M, Woolf AS, Talavera D, Keavney B, Maffia P, Guzik TJ, O'Keefe RT, Trynka G, Samani NJ, Hingorani A, Sampson MG, Morris AP, Charchar FJ, Tomaszewski M. Eales JM, et al. Among authors: xu x. Nat Genet. 2021 May;53(5):630-637. doi: 10.1038/s41588-021-00835-w. Epub 2021 May 6. Nat Genet. 2021. PMID: 33958779
Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study.
Matías-García PR, Wilson R, Guo Q, Zaghlool SB, Eales JM, Xu X, Charchar FJ, Dormer J, Maalmi H, Schlosser P, Elhadad MA, Nano J, Sharma S, Peters A, Fornoni A, Mook-Kanamori DO, Winkelmann J, Danesh J, Di Angelantonio E, Ouwehand WH, Watkins NA, Roberts DJ, Petrera A, Graumann J, Koenig W, Hveem K, Jonasson C, Köttgen A, Butterworth A, Prunotto M, Hauck SM, Herder C, Suhre K, Gieger C, Tomaszewski M, Teumer A, Waldenberger M; Human Kidney Tissue Resource. Matías-García PR, et al. Among authors: xu x. J Am Soc Nephrol. 2021 Jul;32(7):1747-1763. doi: 10.1681/ASN.2020071070. Epub 2021 Jun 16. J Am Soc Nephrol. 2021. PMID: 34135082 Free PMC article.
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