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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
Liu H, Kuang X, Zhang Y, Ye Y, Li J, Liang L, Xie Z, Weng L, Guo J, Li H, Ma F, Chen X, Zhao S, Su J, Yang N, Fang F, Xie Y, Tao J, Zhang J, Chen M, Peng C, Sun L, Zhang X, Liu J, Han L, Xu X, Hung MC, Chen X. Liu H, et al. Among authors: xu x. Cancer Cell. 2020 Mar 16;37(3):324-339.e8. doi: 10.1016/j.ccell.2020.02.006. Cancer Cell. 2020. PMID: 32183950 Free article.
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ. Twyman-Saint Victor C, et al. Among authors: xu b, xu x. Nature. 2015 Apr 16;520(7547):373-7. doi: 10.1038/nature14292. Epub 2015 Mar 9. Nature. 2015. PMID: 25754329 Free PMC article.
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.
Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Chen G, et al. Among authors: xu w, xu x. Nature. 2018 Aug;560(7718):382-386. doi: 10.1038/s41586-018-0392-8. Epub 2018 Aug 8. Nature. 2018. PMID: 30089911 Free PMC article.
Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis.
Liu S, Zhang G, Guo J, Chen X, Lei J, Ze K, Dong L, Dai X, Gao Y, Song D, Ecker BL, Yang R, Feltcher C, Peng K, Feng C, Chen H, Lee RX, Kerestes H, Niu J, Kumar S, Xu W, Zhang J, Wei Z, Martin JS, Liu X, Mills G, Lu Y, Guo W, Sun L, Zhang L, Weeraratna A, Herlyn M, Wei W, Lee FS, Xu X. Liu S, et al. Among authors: xu w, xu x. Nat Commun. 2018 Dec 21;9(1):5426. doi: 10.1038/s41467-018-07126-9. Nat Commun. 2018. PMID: 30575721 Free PMC article.
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.
Beltra JC, Manne S, Abdel-Hakeem MS, Kurachi M, Giles JR, Chen Z, Casella V, Ngiow SF, Khan O, Huang YJ, Yan P, Nzingha K, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Huang AC, Wherry EJ. Beltra JC, et al. Among authors: xu w, xu x. Immunity. 2020 May 19;52(5):825-841.e8. doi: 10.1016/j.immuni.2020.04.014. Epub 2020 May 11. Immunity. 2020. PMID: 32396847 Free PMC article.
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma.
Sharma G, Ojha R, Noguera-Ortega E, Rebecca VW, Attanasio J, Liu S, Piao S, Lee JJ, Nicastri MC, Harper SL, Ronghe A, Jain V, Winkler JD, Speicher DW, Mastio J, Gimotty PA, Xu X, Wherry EJ, Gabrilovich DI, Amaravadi RK. Sharma G, et al. Among authors: xu x. JCI Insight. 2020 Sep 3;5(17):e133225. doi: 10.1172/jci.insight.133225. JCI Insight. 2020. PMID: 32780726 Free PMC article.
The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1.
Li H, Kuang X, Liang L, Ye Y, Zhang Y, Li J, Ma F, Tao J, Lei G, Zhao S, Su J, Yang N, Peng C, Xu X, Hung MC, Han L, Liu H, Liu J, Chen X. Li H, et al. Among authors: xu x. Adv Sci (Weinh). 2020 Nov 27;8(2):2001596. doi: 10.1002/advs.202001596. eCollection 2021 Jan. Adv Sci (Weinh). 2020. PMID: 33510997 Free PMC article.
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