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Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.
Zhang W, Li J, Suzuki K, Qu J, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC. Zhang W, et al. Among authors: xu x. Science. 2015 Jun 5;348(6239):1160-3. doi: 10.1126/science.aaa1356. Epub 2015 Apr 30. Science. 2015. PMID: 25931448 Free PMC article.
Progress and prospects in stem cell therapy.
Xu XL, Yi F, Pan HZ, Duan SL, Ding ZC, Yuan GH, Qu J, Zhang HC, Liu GH. Xu XL, et al. Acta Pharmacol Sin. 2013 Jun;34(6):741-6. doi: 10.1038/aps.2013.77. Acta Pharmacol Sin. 2013. PMID: 23736002 Free PMC article. Review.
Direct reprogramming of porcine fibroblasts to neural progenitor cells.
Xu XL, Yang JP, Fu LN, Ren RT, Yi F, Suzuki K, Liu K, Ding ZC, Qu J, Zhang WQ, Li Y, Yuan TT, Yuan GH, Sui LN, Guan D, Duan SL, Pan HZ, Wang P, Zhu XP, Montserrat N, Li M, Bai RJ, Liu L, Izpisua Belmonte JC, Liu GH. Xu XL, et al. Protein Cell. 2014 Jan;5(1):4-7. doi: 10.1007/s13238-013-0015-y. Protein Cell. 2014. PMID: 24492924 Free PMC article. No abstract available.
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.
Liu GH, Qu J, Suzuki K, Nivet E, Li M, Montserrat N, Yi F, Xu X, Ruiz S, Zhang W, Wagner U, Kim A, Ren B, Li Y, Goebl A, Kim J, Soligalla RD, Dubova I, Thompson J, Yates J 3rd, Esteban CR, Sancho-Martinez I, Izpisua Belmonte JC. Liu GH, et al. Among authors: xu x. Nature. 2012 Nov 22;491(7425):603-7. doi: 10.1038/nature11557. Epub 2012 Oct 17. Nature. 2012. PMID: 23075850 Free PMC article.
Mitochondrial regulation in pluripotent stem cells.
Xu X, Duan S, Yi F, Ocampo A, Liu GH, Izpisua Belmonte JC. Xu X, et al. Cell Metab. 2013 Sep 3;18(3):325-32. doi: 10.1016/j.cmet.2013.06.005. Epub 2013 Jul 11. Cell Metab. 2013. PMID: 23850316 Free article. Review.
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones.
Suzuki K, Yu C, Qu J, Li M, Yao X, Yuan T, Goebl A, Tang S, Ren R, Aizawa E, Zhang F, Xu X, Soligalla RD, Chen F, Kim J, Kim NY, Liao HK, Benner C, Esteban CR, Jin Y, Liu GH, Li Y, Izpisua Belmonte JC. Suzuki K, et al. Among authors: xu x. Cell Stem Cell. 2014 Jul 3;15(1):31-6. doi: 10.1016/j.stem.2014.06.016. Cell Stem Cell. 2014. PMID: 24996168 Free PMC article.
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.
Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, Del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Belmonte JCI. Liu GH, et al. Among authors: xu x. Nat Commun. 2014 Jul 7;5:4330. doi: 10.1038/ncomms5330. Nat Commun. 2014. PMID: 24999918 Free PMC article.
A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells.
Ding Z, Sui L, Ren R, Liu Y, Xu X, Fu L, Bai R, Yuan T, Hao Y, Zhang W, Pan H, Liu W, Yu H, Esteban CR, Yu X, Yang Z, Li J, Wang X, Izpisua Belmonte JC, Liu GH, Yi F, Qu J. Ding Z, et al. Among authors: xu x. Protein Cell. 2015 May;6(5):386-9. doi: 10.1007/s13238-014-0117-1. Protein Cell. 2015. PMID: 25412771 Free PMC article. No abstract available.
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