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A vertebral skeletal stem cell lineage driving metastasis.
Sun J, Hu L, Bok S, Yallowitz AR, Cung M, McCormick J, Zheng LJ, Debnath S, Niu Y, Tan AY, Lalani S, Morse KW, Shinn D, Pajak A, Hammad M, Suhardi VJ, Li Z, Li N, Wang L, Zou W, Mittal V, Bostrom MPG, Xu R, Iyer S, Greenblatt MB. Sun J, et al. Among authors: xu r. Nature. 2023 Sep;621(7979):602-609. doi: 10.1038/s41586-023-06519-1. Epub 2023 Sep 13. Nature. 2023. PMID: 37704733 Free PMC article.
Targeting skeletal endothelium to ameliorate bone loss.
Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim JH, Glimcher LH, Greenblatt MB. Xu R, et al. Nat Med. 2018 Jun;24(6):823-833. doi: 10.1038/s41591-018-0020-z. Epub 2018 May 21. Nat Med. 2018. PMID: 29785024 Free PMC article.
Discovery of a periosteal stem cell mediating intramembranous bone formation.
Debnath S, Yallowitz AR, McCormick J, Lalani S, Zhang T, Xu R, Li N, Liu Y, Yang YS, Eiseman M, Shim JH, Hameed M, Healey JH, Bostrom MP, Landau DA, Greenblatt MB. Debnath S, et al. Among authors: xu r. Nature. 2018 Oct;562(7725):133-139. doi: 10.1038/s41586-018-0554-8. Epub 2018 Sep 24. Nature. 2018. PMID: 30250253 Free PMC article.
Bone protection by inhibition of microRNA-182.
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG, Sood AK, Zhao L, Zhao B. Inoue K, et al. Among authors: xu r. Nat Commun. 2018 Oct 5;9(1):4108. doi: 10.1038/s41467-018-06446-0. Nat Commun. 2018. PMID: 30291236 Free PMC article.
Osteoclasts are not a source of SLIT3.
Li N, Inoue K, Sun J, Niu Y, Lalani S, Yallowitz A, Yang X, Zhang C, Shen R, Zhao B, Xu R, Greenblatt MB. Li N, et al. Among authors: xu r. Bone Res. 2020 Feb 19;8:11. doi: 10.1038/s41413-020-0086-3. eCollection 2020. Bone Res. 2020. PMID: 32133214 Free PMC article.
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. Kim JM, et al. Among authors: xu r. Nat Commun. 2020 May 8;11(1):2289. doi: 10.1038/s41467-020-16038-6. Nat Commun. 2020. PMID: 32385263 Free PMC article.
Alendronate enhances osseointegration in a murine implant model.
Vertesich K, Sosa BR, Niu Y, Ji G, Suhardi V, Turajane K, Mun S, Xu R, Windhager R, Park-Min KH, Greenblatt MB, Bostrom MP, Yang X. Vertesich K, et al. Among authors: xu r. J Orthop Res. 2021 Apr;39(4):719-726. doi: 10.1002/jor.24853. Epub 2020 Sep 19. J Orthop Res. 2021. PMID: 32915488 Free PMC article.
MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.
Bok S, Shin DY, Yallowitz AR, Eiseman M, Cung M, Xu R, Li N, Sun J, Williams AL, Scott JE, Su B, Shim JH, Greenblatt MB. Bok S, et al. Among authors: xu r. Nat Commun. 2020 Nov 11;11(1):5704. doi: 10.1038/s41467-020-19555-6. Nat Commun. 2020. PMID: 33177525 Free PMC article.
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