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Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes.
Smith EE, Shoamanesh A, Xu L, Heenan L, Saad F, Colorado P, Chen CH, Lemmens R, De Marchis GM, Caso V, Masjuan J, Hirano T, Milanov I, Campbell BCV, Mas JL, Connolly SJ, Mundl H, Hart RG; PACIFIC-Stroke Steering Committee and Investigators. Smith EE, et al. Among authors: xu l. Stroke. 2024 Feb;55(2):392-402. doi: 10.1161/STROKEAHA.123.043198. Epub 2024 Jan 4. Stroke. 2024. PMID: 38174569 Clinical Trial.
Restart of Anticoagulant Therapy and Risk of Thrombosis, Rebleeding, and Death after Factor Xa Inhibitor Reversal in Major Bleeding Patients.
Milling TJ Jr, King B, Yue P, Middeldorp S, Beyer-Westendorf J, Eikelboom JW, Crowther M, Xu L, Verhamme P, Siegal DM, Connolly SJ; ANNEXA-4 Investigators. Milling TJ Jr, et al. Among authors: xu l. Thromb Haemost. 2021 Aug;121(8):1097-1106. doi: 10.1055/a-1400-6159. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33634446 Free PMC article.
Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy.
Demchuk AM, Yue P, Zotova E, Nakamya J, Xu L, Milling TJ Jr, Ohara T, Goldstein JN, Middeldorp S, Verhamme P, Lopez-Sendon JL, Conley PB, Curnutte JT, Eikelboom JW, Crowther M, Connolly SJ; ANNEXA-4 Investigators. Demchuk AM, et al. Among authors: xu l. Stroke. 2021 Jun;52(6):2096-2105. doi: 10.1161/STROKEAHA.120.030565. Epub 2021 May 10. Stroke. 2021. PMID: 33966491 Free PMC article. Clinical Trial.
Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial.
Shoamanesh A, Mundl H, Smith EE, Masjuan J, Milanov I, Hirano T, Agafina A, Campbell B, Caso V, Mas JL, Dong Q, Turcani P, Christensen H, Ferro JM, Veltkamp R, Mikulik R, De Marchis GM, Robinson T, Lemmens R, Stepien A, Greisenegger S, Roine R, Csiba L, Khatri P, Coutinho J, Lindgren AG, Demchuk AM, Colorado P, Kirsch B, Neumann C, Heenan L, Xu L, Connolly SJ, Hart RG; PACIFIC-Stroke Investigators. Shoamanesh A, et al. Among authors: xu l. Lancet. 2022 Sep 24;400(10357):997-1007. doi: 10.1016/S0140-6736(22)01588-4. Epub 2022 Sep 2. Lancet. 2022. PMID: 36063821 Clinical Trial.
Bleeding Risk Prediction in Patients Treated with Antithrombotic Drugs According to the Anatomic Site of Bleeding, Indication for Treatment, and Time Since Treatment Initiation.
Bhagirath V, Kovalova T, Wang J, Xu L, Bangdiwala SI, O'Donnell M, Shoamanesh A, Bosch J, Coppolecchia R, Vaitsiakhovich T, Kleinjung F, Mundl H, Eikelboom J. Bhagirath V, et al. Among authors: xu l. TH Open. 2024 Mar 18;8(1):e121-e131. doi: 10.1055/a-2259-1134. eCollection 2024 Jan. TH Open. 2024. PMID: 38505564 Free PMC article.
The Efficacy and Safety of Andexanet Alfa in Patients With Acute Gastrointestinal Bleeding While Taking Factor Xa Inhibitors: An ANNEXA-4 Subanalysis.
Siegal DM, Forbes N, Eikelboom J, Beyer-Westendorf J, Cohen AT, Xu L, Connolly SJ, Crowther M. Siegal DM, et al. Among authors: xu l. Circulation. 2024 Apr 16;149(16):1315-1318. doi: 10.1161/CIRCULATIONAHA.123.066933. Epub 2024 Apr 15. Circulation. 2024. PMID: 38620086 Free PMC article. No abstract available.
Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors.
Milling TJ Jr, Middeldorp S, Xu L, Koch B, Demchuk A, Eikelboom JW, Verhamme P, Cohen AT, Beyer-Westendorf J, Gibson CM, Lopez-Sendon J, Crowther M, Shoamanesh A, Coppens M, Schmidt J, Albaladejo P, Connolly SJ; ANNEXA-4 Investigators. Milling TJ Jr, et al. Among authors: xu l. Circulation. 2023 Mar 28;147(13):1026-1038. doi: 10.1161/CIRCULATIONAHA.121.057844. Epub 2023 Feb 20. Circulation. 2023. PMID: 36802876 Free article. Clinical Trial.
LVS-HARMED Risk Score for Incident Heart Failure in Patients With Atrial Fibrillation Who Present to the Emergency Department: Data from a World-Wide Registry.
Johnson LSB, Oldgren J, Barrett TW, McNaughton CD, Wong JA, McIntyre WF, Freeman CL, Murphy L, Engström G, Ezekowitz M, Connolly SJ, Xu L, Nakamya J, Conen D, Bangdiwala SI, Yusuf S, Healey JS. Johnson LSB, et al. Among authors: xu l. J Am Heart Assoc. 2021 Sep 21;10(18):e017735. doi: 10.1161/JAHA.120.017735. Epub 2021 Sep 13. J Am Heart Assoc. 2021. PMID: 34514842 Free PMC article.
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