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Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51.
Tao L, Zhou Y, Pan X, Luo Y, Qiu J, Zhou X, Chen Z, Li Y, Xu L, Zhou Y, Zuo Z, Liu C, Wang L, Liu X, Tian X, Su N, Yang Z, Zhang Y, Gou K, Sang N, Liu H, Zou J, Xiao Y, Zhong X, Xu J, Yang X, Xiao K, Liu Y, Yang S, Peng Y, Han J, Cen X, Zhao Y. Tao L, et al. Among authors: xu l, xu j. Nat Commun. 2023 Nov 16;14(1):7430. doi: 10.1038/s41467-023-42850-x. Nat Commun. 2023. PMID: 37973845 Free PMC article.
The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts.
Zhao L, Wang W, Huang S, Yang Z, Xu L, Yang Q, Zhou X, Wang J, Shen Q, Wang C, Le X, Feng M, Zhou N, Lau WB, Lau B, Yao S, Yi T, Wang X, Zhao X, Wei Y, Zhou S. Zhao L, et al. Among authors: xu l. Genome Biol. 2018 Mar 16;19(1):35. doi: 10.1186/s13059-018-1412-6. Genome Biol. 2018. PMID: 29548303 Free PMC article.
Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
Zhao L, Huang S, Mei S, Yang Z, Xu L, Zhou N, Yang Q, Shen Q, Wang W, Le X, Lau WB, Lau B, Wang X, Yi T, Zhao X, Wei Y, Warner M, Gustafsson JÅ, Zhou S. Zhao L, et al. Among authors: xu l. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3673-E3681. doi: 10.1073/pnas.1803291115. Epub 2018 Mar 28. Proc Natl Acad Sci U S A. 2018. PMID: 29592953 Free PMC article.
Epigenetics in ovarian cancer: premise, properties, and perspectives.
Yang Q, Yang Y, Zhou N, Tang K, Lau WB, Lau B, Wang W, Xu L, Yang Z, Huang S, Wang X, Yi T, Zhao X, Wei Y, Wang H, Zhao L, Zhou S. Yang Q, et al. Among authors: xu l. Mol Cancer. 2018 Jul 31;17(1):109. doi: 10.1186/s12943-018-0855-4. Mol Cancer. 2018. PMID: 30064416 Free PMC article. Review.
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
Zhao L, Qiu Z, Yang Z, Xu L, Pearce TM, Wu Q, Yang K, Li F, Saulnier O, Fei F, Yu H, Gimple RC, Varadharajan V, Liu J, Hendrikse LD, Fong V, Wang W, Zhang J, Lv D, Lee D, Lehrich BM, Jin C, Ouyang L, Dixit D, Wu H, Wang X, Sloan AE, Wang X, Huan T, Mark Brown J, Goldman SA, Taylor MD, Zhou S, Rich JN. Zhao L, et al. Among authors: xu l. Nat Cancer. 2024 Jan;5(1):147-166. doi: 10.1038/s43018-023-00658-0. Epub 2024 Jan 3. Nat Cancer. 2024. PMID: 38172338
Tumor microenvironment: The culprit for ovarian cancer metastasis?
Luo Z, Wang Q, Lau WB, Lau B, Xu L, Zhao L, Yang H, Feng M, Xuan Y, Yang Y, Lei L, Wang C, Yi T, Zhao X, Wei Y, Zhou S. Luo Z, et al. Among authors: xu l. Cancer Lett. 2016 Jul 28;377(2):174-82. doi: 10.1016/j.canlet.2016.04.038. Epub 2016 Apr 27. Cancer Lett. 2016. PMID: 27131957 Review.
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