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Transcriptional Regulation of Antiviral Interferon-Stimulated Genes.
Wang W, Xu L, Su J, Peppelenbosch MP, Pan Q. Wang W, et al. Among authors: xu l. Trends Microbiol. 2017 Jul;25(7):573-584. doi: 10.1016/j.tim.2017.01.001. Epub 2017 Jan 27. Trends Microbiol. 2017. PMID: 28139375 Free PMC article. Review.
IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genes.
Xu L, Zhou X, Wang W, Wang Y, Yin Y, Laan LJ, Sprengers D, Metselaar HJ, Peppelenbosch MP, Pan Q. Xu L, et al. FASEB J. 2016 Oct;30(10):3352-3367. doi: 10.1096/fj.201600356R. Epub 2016 Jun 21. FASEB J. 2016. PMID: 27328944
We demonstrated that IRF1 effectively inhibits HEV replication through the activation of the JAK-STAT pathway, and the subsequent transcription of antiviral ISGs, but independent of IFN production.-Xu, L., Zhou, X., Wang, W., Wang, Y., Yin, Y., van der Laan, L …
We demonstrated that IRF1 effectively inhibits HEV replication through the activation of the JAK-STAT pathway, and the subsequent transcript …
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