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Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1.
Tao L, Yang G, Sun T, Jie Tao, Zhu C, Yu H, Cheng Y, Yang Z, Xu M, Jiang Y, Zhang W, Wang Z, Ma W, Wu L, Xue D, Wang D, Yang W, Zhao Y, Horsefield S, Kobe B, Zhang Z, Tang Z, Li Q, Zhai Q, Dooley S, Seki E, Liu P, Xu J, Chen H, Liu C. Tao L, et al. Among authors: xu m, xu j. J Hepatol. 2023 Apr;78(4):805-819. doi: 10.1016/j.jhep.2022.12.031. Epub 2023 Jan 18. J Hepatol. 2023. PMID: 36669703
Direct SUMOylation of M1 muscarinic acetylcholine receptor increases its ligand-binding affinity and signal transduction.
Xu J, Tan P, Li H, Cui Y, Qiu Y, Wang H, Zhang X, Li J, Zhu L, Zhou W, Chen H. Xu J, et al. FASEB J. 2019 Mar;33(3):3237-3251. doi: 10.1096/fj.201800936R. Epub 2018 Nov 8. FASEB J. 2019. PMID: 30407877
Our results provide evidence that M1 SUMOylation is an important PTM involved in regulation of the affinity for agonists and for activation of signaling pathways.-Xu, J., Tan, P., Li, H., Cui, Y., Qiu, Y., Wang, H., Zhang, X., Li, J., Zhu, L., Zhou, W., Chen, …
Our results provide evidence that M1 SUMOylation is an important PTM involved in regulation of the affinity for agonists and for activation …
M1 muscarinic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 via a signaling pathway linking cAMP-PKA and PI3K-Akt.
Zhao LX, Ge YH, Li JB, Xiong CH, Law PY, Xu JR, Qiu Y, Chen HZ. Zhao LX, et al. FASEB J. 2019 May;33(5):6622-6631. doi: 10.1096/fj.201802351R. Epub 2019 Feb 22. FASEB J. 2019. PMID: 30794430
Taken together, these data demonstrate that M1 receptor activation induces membrane insertion of GluA1 via a signaling linking cAMP-PKA and PI3K-Akt-mTOR pathways but is irrelevant to protein synthesis.-Zhao, L.-X., Ge, Y.-H., Li, J.-B., Xiong, C.-H., Law, P.-Y., Xu …
Taken together, these data demonstrate that M1 receptor activation induces membrane insertion of GluA1 via a signaling linking cAMP-PKA and …
61,898 results
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