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Blocking LAIR1 signaling in immune cells inhibits tumor development.
Xie J, Gui X, Deng M, Chen H, Chen Y, Liu X, Ku Z, Tan L, Huang R, He Y, Zhang B, Lewis C, Chen K, Xu L, Xu J, Huang T, Liao XC, Zhang N, An Z, Zhang CC. Xie J, et al. Among authors: xu l, xu j. Front Immunol. 2022 Sep 21;13:996026. doi: 10.3389/fimmu.2022.996026. eCollection 2022. Front Immunol. 2022. PMID: 36211388 Free PMC article.
Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia.
Gu Z, Liu Y, Zhang Y, Cao H, Lyu J, Wang X, Wylie A, Newkirk SJ, Jones AE, Lee M Jr, Botten GA, Deng M, Dickerson KE, Zhang CC, An W, Abrams JM, Xu J. Gu Z, et al. Among authors: xu j. Nat Genet. 2021 May;53(5):672-682. doi: 10.1038/s41588-021-00829-8. Epub 2021 Apr 8. Nat Genet. 2021. PMID: 33833453 Free PMC article.
Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9.
Zhang LS, Kang X, Lu J, Zhang Y, Wu X, Wu G, Zheng J, Tuladhar R, Shi H, Wang Q, Morlock L, Yao H, Huang LJ, Maire P, Kim J, Williams N, Xu J, Chen C, Zhang CC, Lum L. Zhang LS, et al. Among authors: xu j. EBioMedicine. 2019 Jan;39:145-158. doi: 10.1016/j.ebiom.2018.11.039. Epub 2018 Dec 6. EBioMedicine. 2019. PMID: 30528456 Free PMC article.
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