Xu H - Search Results

1

Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.

Chen Q, She J, Zeng W, Guo J, Xu H, Bai XC, Jiang Y. Chen Q, et al. Among authors: xu h. Nature. 2017 Oct 19;550(7676):415-418. doi: 10.1038/nature24035. Epub 2017 Oct 11. Nature. 2017. PMID: 29019981 Free PMC article.

2

TRPV3 is a calcium-permeable temperature-sensitive cation channel.

Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. Xu H, et al. Nature. 2002 Jul 11;418(6894):181-6. doi: 10.1038/nature00882. Epub 2002 Jun 23. Nature. 2002. PMID: 12077604

3

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel.

Dong XP, Cheng X, Mills E, Delling M, Wang F, Kurz T, Xu H. Dong XP, et al. Among authors: xu h. Nature. 2008 Oct 16;455(7215):992-6. doi: 10.1038/nature07311. Epub 2008 Sep 14. Nature. 2008. PMID: 18794901 Free PMC article.

4

Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.

Dong XP, Wang X, Shen D, Chen S, Liu M, Wang Y, Mills E, Cheng X, Delling M, Xu H. Dong XP, et al. Among authors: xu h. J Biol Chem. 2009 Nov 13;284(46):32040-52. doi: 10.1074/jbc.M109.037184. Epub 2009 Jul 28. J Biol Chem. 2009. PMID: 19638346 Free PMC article.

5

Mucolipins: Intracellular TRPML1-3 channels.

Cheng X, Shen D, Samie M, Xu H. Cheng X, et al. Among authors: xu h. FEBS Lett. 2010 May 17;584(10):2013-21. doi: 10.1016/j.febslet.2009.12.056. Epub 2010 Jan 13. FEBS Lett. 2010. PMID: 20074572 Free PMC article. Review.

6

PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.

Dong XP, Shen D, Wang X, Dawson T, Li X, Zhang Q, Cheng X, Zhang Y, Weisman LS, Delling M, Xu H. Dong XP, et al. Among authors: xu h. Nat Commun. 2010 Jul 13;1(4):38. doi: 10.1038/ncomms1037. Nat Commun. 2010. PMID: 20802798 Free PMC article.

7

Pairing phosphoinositides with calcium ions in endolysosomal dynamics: phosphoinositides control the direction and specificity of membrane trafficking by regulating the activity of calcium channels in the endolysosomes.

Shen D, Wang X, Xu H. Shen D, et al. Among authors: xu h. Bioessays. 2011 Jun;33(6):448-57. doi: 10.1002/bies.201000152. Epub 2011 Apr 28. Bioessays. 2011. PMID: 21538413 Free PMC article. Review.

8

Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release.

Shen D, Wang X, Li X, Zhang X, Yao Z, Dibble S, Dong XP, Yu T, Lieberman AP, Showalter HD, Xu H. Shen D, et al. Among authors: xu h. Nat Commun. 2012 Mar 13;3:731. doi: 10.1038/ncomms1735. Nat Commun. 2012. PMID: 22415822 Free PMC article.

9

Phosphoinositide isoforms determine compartment-specific ion channel activity.

Zhang X, Li X, Xu H. Zhang X, et al. Among authors: xu h. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11384-9. doi: 10.1073/pnas.1202194109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733759 Free PMC article.

10

A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis.

Samie M, Wang X, Zhang X, Goschka A, Li X, Cheng X, Gregg E, Azar M, Zhuo Y, Garrity AG, Gao Q, Slaugenhaupt S, Pickel J, Zolov SN, Weisman LS, Lenk GM, Titus S, Bryant-Genevier M, Southall N, Juan M, Ferrer M, Xu H. Samie M, et al. Among authors: xu h. Dev Cell. 2013 Sep 16;26(5):511-24. doi: 10.1016/j.devcel.2013.08.003. Epub 2013 Aug 29. Dev Cell. 2013. PMID: 23993788 Free PMC article.

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