Xu H - Search Results

1

Can corruption of chromosome cohesion create a conduit to cancer?

Xu H, Tomaszewski JM, McKay MJ. Xu H, et al. Nat Rev Cancer. 2011 Mar;11(3):199-210. doi: 10.1038/nrc3018. Epub 2011 Feb 17. Nat Rev Cancer. 2011. PMID: 21326324 Review.

2

Caspase proteolysis of the cohesin component RAD21 promotes apoptosis.

Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL. Chen F, et al. Among authors: xu h. J Biol Chem. 2002 May 10;277(19):16775-81. doi: 10.1074/jbc.M201322200. Epub 2002 Mar 1. J Biol Chem. 2002. PMID: 11875078 Free article.

3

Conserved disruptions in the predicted coiled-coil domains of eukaryotic SMC complexes: implications for structure and function.

Beasley M, Xu H, Warren W, McKay M. Beasley M, et al. Among authors: xu h. Genome Res. 2002 Aug;12(8):1201-9. doi: 10.1101/gr107302. Genome Res. 2002. PMID: 12176928 Free PMC article.

4

A new role for the mitotic RAD21/SCC1 cohesin in meiotic chromosome cohesion and segregation in the mouse.

Xu H, Beasley M, Verschoor S, Inselman A, Handel MA, McKay MJ. Xu H, et al. EMBO Rep. 2004 Apr;5(4):378-84. doi: 10.1038/sj.embor.7400121. Epub 2004 Mar 19. EMBO Rep. 2004. PMID: 15031719 Free PMC article.

5

Absence of mouse REC8 cohesin promotes synapsis of sister chromatids in meiosis.

Xu H, Beasley MD, Warren WD, van der Horst GT, McKay MJ. Xu H, et al. Dev Cell. 2005 Jun;8(6):949-61. doi: 10.1016/j.devcel.2005.03.018. Dev Cell. 2005. PMID: 15935783 Free article.

6

Resolution of chiasmata in oocytes requires separase-mediated proteolysis.

Kudo NR, Wassmann K, Anger M, Schuh M, Wirth KG, Xu H, Helmhart W, Kudo H, McKay M, Maro B, Ellenberg J, de Boer P, Nasmyth K. Kudo NR, et al. Among authors: xu h. Cell. 2006 Jul 14;126(1):135-46. doi: 10.1016/j.cell.2006.05.033. Cell. 2006. PMID: 16839882 Free article.

7

Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase.

Wojtasz L, Daniel K, Roig I, Bolcun-Filas E, Xu H, Boonsanay V, Eckmann CR, Cooke HJ, Jasin M, Keeney S, McKay MJ, Toth A. Wojtasz L, et al. Among authors: xu h. PLoS Genet. 2009 Oct;5(10):e1000702. doi: 10.1371/journal.pgen.1000702. Epub 2009 Oct 23. PLoS Genet. 2009. PMID: 19851446 Free PMC article.

8

MAb 806 enhances the efficacy of ionizing radiation in glioma xenografts expressing the de2-7 epidermal growth factor receptor.

Johns TG, McKay MJ, Cvrljevic AN, Gan HK, Taylor C, Xu H, Smyth FE, Scott AM. Johns TG, et al. Among authors: xu h. Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):572-8. doi: 10.1016/j.ijrobp.2010.03.027. Epub 2010 Jul 16. Int J Radiat Oncol Biol Phys. 2010. PMID: 20638193

9

Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice.

Xu H, Balakrishnan K, Malaterre J, Beasley M, Yan Y, Essers J, Appeldoorn E, Tomaszewski JM, Vazquez M, Verschoor S, Lavin MF, Bertoncello I, Ramsay RG, McKay MJ. Xu H, et al. PLoS One. 2010 Aug 12;5(8):e12112. doi: 10.1371/journal.pone.0012112. PLoS One. 2010. PMID: 20711430 Free PMC article.

10

Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers.

Xu H, Yan M, Patra J, Natrajan R, Yan Y, Swagemakers S, Tomaszewski JM, Verschoor S, Millar EK, van der Spek P, Reis-Filho JS, Ramsay RG, O'Toole SA, McNeil CM, Sutherland RL, McKay MJ, Fox SB. Xu H, et al. Breast Cancer Res. 2011 Jan 21;13(1):R9. doi: 10.1186/bcr2814. Breast Cancer Res. 2011. PMID: 21255398 Free PMC article.

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