Xu F - Search Results

1

VEGF signal system: the application of antiangiogenesis.

Liang X, Xu F, Li X, Ma C, Zhang Y, Xu W. Liang X, et al. Among authors: xu f, xu w. Curr Med Chem. 2014 Mar;21(7):894-910. doi: 10.2174/09298673113206660264. Curr Med Chem. 2014. PMID: 24059233 Review.

2

Design, synthesis and preliminary activity evaluation of novel L-lysine derivatives as aminopeptidase N/CD13 inhibitors.

Wang Q, Xu F, Mou J, Zhang J, Shang L, Luan Y, Yuan Y, Liu Y, Li M, Fang H, Wang B, Xu W. Wang Q, et al. Among authors: xu f, xu w. Protein Pept Lett. 2010 Jul;17(7):847-53. doi: 10.2174/092986610791306661. Protein Pept Lett. 2010. PMID: 20156182

3

Discovery of novel vascular endothelial growth factor receptor 2 inhibitors: a virtual screening approach.

Zhang L, Wang X, Feng J, Jia Y, Xu F, Xu W. Zhang L, et al. Among authors: xu f, xu w. Chem Biol Drug Des. 2012 Dec;80(6):893-901. doi: 10.1111/cbdd.12036. Chem Biol Drug Des. 2012. PMID: 22913881

4

Synthesis and biological evaluation of N-(4-hydroxy-3-mercaptonaphthalen-1-yl)amides as inhibitors of angiogenesis and tumor growth.

Xu F, Jia Y, Wen Q, Wang X, Zhang L, Zhang Y, Yang K, Xu W. Xu F, et al. Among authors: xu w. Eur J Med Chem. 2013 Jun;64:377-88. doi: 10.1016/j.ejmech.2013.03.043. Epub 2013 Apr 6. Eur J Med Chem. 2013. PMID: 23644219

5

Discovery of 4-amino-2-(thio)phenol derivatives as novel protein kinase and angiogenesis inhibitors for the treatment of cancer: synthesis and biological evaluation. Part II.

Xu F, Zhang L, Jia Y, Wang X, Li X, Wen Q, Zhang Y, Xu W. Xu F, et al. Among authors: xu w. Eur J Med Chem. 2013 Nov;69:191-200. doi: 10.1016/j.ejmech.2013.07.056. Epub 2013 Aug 29. Eur J Med Chem. 2013. PMID: 24036042

6

Design, synthesis and biological evaluation of pazopanib derivatives as antitumor agents.

Jia Y, Zhang J, Feng J, Xu F, Pan H, Xu W. Jia Y, et al. Among authors: xu f, xu w. Chem Biol Drug Des. 2014 Mar;83(3):306-16. doi: 10.1111/cbdd.12243. Epub 2014 Feb 1. Chem Biol Drug Des. 2014. PMID: 24119291

7

Discovery of N-(3-((7H-purin-6-yl)thio)-4-hydroxynaphthalen-1-yl)-sulfonamide derivatives as novel protein kinase and angiogenesis inhibitors for the treatment of cancer: Synthesis and biological evaluation. Part III.

Xu F, Xu H, Wang X, Zhang L, Wen Q, Zhang Y, Xu W. Xu F, et al. Among authors: xu w, xu h. Bioorg Med Chem. 2014 Feb 15;22(4):1487-95. doi: 10.1016/j.bmc.2013.11.052. Epub 2013 Dec 8. Bioorg Med Chem. 2014. PMID: 24440479

8

Trend of histone deacetylase inhibitors in cancer therapy: isoform selectivity or multitargeted strategy.

Zhang L, Han Y, Jiang Q, Wang C, Chen X, Li X, Xu F, Jiang Y, Wang Q, Xu W. Zhang L, et al. Among authors: xu f, xu w. Med Res Rev. 2015 Jan;35(1):63-84. doi: 10.1002/med.21320. Epub 2014 Apr 29. Med Res Rev. 2015. PMID: 24782318 Review.

9

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression.

Zhou B, Hu J, Xu F, Chen Z, Bai L, Fernandez-Salas E, Lin M, Liu L, Yang CY, Zhao Y, McEachern D, Przybranowski S, Wen B, Sun D, Wang S. Zhou B, et al. Among authors: xu f. J Med Chem. 2018 Jan 25;61(2):462-481. doi: 10.1021/acs.jmedchem.6b01816. Epub 2017 Mar 24. J Med Chem. 2018. PMID: 28339196 Free PMC article.

10

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression.

Qin C, Hu Y, Zhou B, Fernandez-Salas E, Yang CY, Liu L, McEachern D, Przybranowski S, Wang M, Stuckey J, Meagher J, Bai L, Chen Z, Lin M, Yang J, Ziazadeh DN, Xu F, Hu J, Xiang W, Huang L, Li S, Wen B, Sun D, Wang S. Qin C, et al. Among authors: xu f. J Med Chem. 2018 Aug 9;61(15):6685-6704. doi: 10.1021/acs.jmedchem.8b00506. Epub 2018 Jul 18. J Med Chem. 2018. PMID: 30019901 Free PMC article.

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