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Vaccine design via antigen reorientation.
Xu D, Carter JJ, Li C, Utz A, Weidenbacher PAB, Tang S, Sanyal M, Pulendran B, Barnes CO, Kim PS. Xu D, et al. Nat Chem Biol. 2024 Jan 15. doi: 10.1038/s41589-023-01529-6. Online ahead of print. Nat Chem Biol. 2024. PMID: 38225471
Design of universal Ebola virus vaccine candidates via immunofocusing.
Xu D, Powell AE, Utz A, Sanyal M, Do J, Patten JJ, Moliva JI, Sullivan NJ, Davey RA, Kim PS. Xu D, et al. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2316960121. doi: 10.1073/pnas.2316960121. Epub 2024 Feb 6. Proc Natl Acad Sci U S A. 2024. PMID: 38319964 Free PMC article.
Interstitial macrophages are a focus of viral takeover and inflammation in COVID-19 initiation in human lung.
Wu TT, Travaglini KJ, Rustagi A, Xu D, Zhang Y, Andronov L, Jang S, Gillich A, Dehghannasiri R, Martínez-Colón GJ, Beck A, Liu DD, Wilk AJ, Morri M, Trope WL, Bierman R, Weissman IL, Shrager JB, Quake SR, Kuo CS, Salzman J, Moerner WE, Kim PS, Blish CA, Krasnow MA. Wu TT, et al. Among authors: xu d. J Exp Med. 2024 Jun 3;221(6):e20232192. doi: 10.1084/jem.20232192. Epub 2024 Apr 10. J Exp Med. 2024. PMID: 38597954 Free PMC article.
Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice.
Wen J, Wu D, Qin M, Liu C, Wang L, Xu D, Vinters HV, Liu Y, Kranz E, Guan X, Sun G, Sun X, Lee Y, Martinez-Maza O, Widney D, Lu Y, Chen ISY, Kamata M. Wen J, et al. Among authors: xu d. Nat Biomed Eng. 2019 Sep;3(9):706-716. doi: 10.1038/s41551-019-0434-z. Epub 2019 Aug 5. Nat Biomed Eng. 2019. PMID: 31384008 Free PMC article.
A single-arm, multicenter, phase 2 clinical study of recombinant humanized anti-HER2 monoclonal antibody-MMAE conjugate (MRG002) in HER2-positive unresectable locally advanced or metastatic urothelial carcinoma.
Qu W, Fu C, Han W, Luo H, Quan J, Chen L, Liao Y, Hu C, Hu H, Niu Y, Xu D, Chen M, Chen J, Liu Y, Chen G, Luo Z, Shi B, Sun Y, Zhou F, Zhou A. Qu W, et al. Among authors: xu d. Eur J Cancer. 2024 May 10;205:114096. doi: 10.1016/j.ejca.2024.114096. Online ahead of print. Eur J Cancer. 2024. PMID: 38772302
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