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Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Weaver JD, Stack EC, Buggé JA, Hu C, McGrath L, Mueller A, Wong M, Klebanov B, Rahman T, Kaufman R, Fregeau C, Spaulding V, Priess M, Legendre K, Jaffe S, Upadhyay D, Singh A, Xu CA, Krukenberg K, Zhang Y, Ezzyat Y, Saddier Axe D, Kuhne MR, Meehl MA, Shaffer DR, Weist BM, Wiederschain D, Depis F, Gostissa M. Weaver JD, et al. Among authors: xu ca. Oncoimmunology. 2022 Nov 4;11(1):2141007. doi: 10.1080/2162402X.2022.2141007. eCollection 2022. Oncoimmunology. 2022. PMID: 36352891 Free PMC article.
L445P mutation on heavy chain stabilizes IgG4 under acidic conditions.
Xu CA, Feng AZ, Ramineni CK, Wallace MR, Culyba EK, Guay KP, Mehta K, Mabry R, Farrand S, Xu J, Feng J. Xu CA, et al. Among authors: xu j. MAbs. 2019 Oct;11(7):1289-1299. doi: 10.1080/19420862.2019.1631116. Epub 2019 Jul 11. MAbs. 2019. PMID: 31199179 Free PMC article.
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.
Gargaro M, Scalisi G, Manni G, Briseño CG, Bagadia P, Durai V, Theisen DJ, Kim S, Castelli M, Xu CA, Meyer Zu Hörste G, Servillo G, Della Fazia MA, Mencarelli G, Ricciuti D, Padiglioni E, Giacchè N, Colliva C, Pellicciari R, Calvitti M, Zelante T, Fuchs D, Orabona C, Boon L, Bessede A, Colonna M, Puccetti P, Murphy TL, Murphy KM, Fallarino F. Gargaro M, et al. Among authors: xu ca. Immunity. 2022 Jun 14;55(6):1032-1050.e14. doi: 10.1016/j.immuni.2022.05.013. Immunity. 2022. PMID: 35704993 Free PMC article.
Clinical implications of exosome-derived noncoding RNAs in liver.
Zhou ZW, Zheng W, Xiang Z, Ye CS, Yin QQ, Wang SH, Xu CA, Wu WH, Hui TC, Wu QQ, Zhao LY, Pan HY, Xu KY. Zhou ZW, et al. Among authors: xu ca. Lab Invest. 2022 May;102(5):464-473. doi: 10.1038/s41374-021-00723-1. Epub 2022 Jan 10. Lab Invest. 2022. PMID: 35013531 Free article. Review.
21 results