Xu C - Search Results

1

Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors.

Fan Z, Tian Y, Chen Z, Liu L, Zhou Q, He J, Coleman J, Dong C, Li N, Huang J, Xu C, Zhang Z, Gao S, Zhou P, Ding K, Chen L. Fan Z, et al. Among authors: xu c. EMBO Mol Med. 2020 Jun 8;12(6):e11571. doi: 10.15252/emmm.201911571. Epub 2020 May 11. EMBO Mol Med. 2020. PMID: 32391629 Free PMC article.

2

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.

Yang W, Bai Y, Xiong Y, Zhang J, Chen S, Zheng X, Meng X, Li L, Wang J, Xu C, Yan C, Wang L, Chang CC, Chang TY, Zhang T, Zhou P, Song BL, Liu W, Sun SC, Liu X, Li BL, Xu C. Yang W, et al. Among authors: xu c. Nature. 2016 Mar 31;531(7596):651-5. doi: 10.1038/nature17412. Epub 2016 Mar 16. Nature. 2016. PMID: 26982734 Free PMC article.

3

FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.

Meng X, Liu X, Guo X, Jiang S, Chen T, Hu Z, Liu H, Bai Y, Xue M, Hu R, Sun SC, Liu X, Zhou P, Huang X, Wei L, Yang W, Xu C. Meng X, et al. Among authors: xu c. Nature. 2018 Dec;564(7734):130-135. doi: 10.1038/s41586-018-0756-0. Epub 2018 Nov 28. Nature. 2018. PMID: 30487606

4

PD-1: A Driver or Passenger of T Cell Exhaustion?

He X, Xu C. He X, et al. Among authors: xu c. Mol Cell. 2020 Mar 5;77(5):930-931. doi: 10.1016/j.molcel.2020.02.013. Mol Cell. 2020. PMID: 32142689 Free article.

5

Shaping immune landscape of colorectal cancer by cholesterol metabolites.

Bai Y, Li T, Wang Q, You W, Yang H, Xu X, Li Z, Zhang Y, Yan C, Yang L, Qiu J, Liu Y, Chen S, Wang D, Huang B, Liu K, Song BL, Wang Z, Li K, Liu X, Wang G, Yang W, Chen J, Hao P, Zhang Z, Wang Z, Zhu ZJ, Xu C. Bai Y, et al. Among authors: xu c, xu x. EMBO Mol Med. 2024 Feb;16(2):334-360. doi: 10.1038/s44321-023-00015-9. Epub 2024 Jan 2. EMBO Mol Med. 2024. PMID: 38177537 Free PMC article.

6

Immune checkpoint signaling and cancer immunotherapy.

He X, Xu C. He X, et al. Among authors: xu c. Cell Res. 2020 Aug;30(8):660-669. doi: 10.1038/s41422-020-0343-4. Epub 2020 May 28. Cell Res. 2020. PMID: 32467592 Free PMC article. Review.

7

PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.

Wen M, Cao Y, Wu B, Xiao T, Cao R, Wang Q, Liu X, Xue H, Yu Y, Lin J, Xu C, Xu J, OuYang B. Wen M, et al. Among authors: xu c, xu j. Nat Commun. 2021 Aug 24;12(1):5106. doi: 10.1038/s41467-021-25416-7. Nat Commun. 2021. PMID: 34429434 Free PMC article.

8

Disulfiram bolsters T-cell anti-tumor immunity through direct activation of LCK-mediated TCR signaling.

Wang Q, Zhu T, Miao N, Qu Y, Wang Z, Chao Y, Wang J, Wu W, Xu X, Xu C, Xia L, Wang F. Wang Q, et al. Among authors: xu c, xu x. EMBO J. 2022 Aug 16;41(16):e110636. doi: 10.15252/embj.2022110636. Epub 2022 May 31. EMBO J. 2022. PMID: 35638332 Free PMC article.

9

Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling.

Li L, Guo X, Shi X, Li C, Wu W, Yan C, Wang H, Li H, Xu C. Li L, et al. Among authors: xu c. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5891-E5899. doi: 10.1073/pnas.1701990114. Epub 2017 Jun 28. Proc Natl Acad Sci U S A. 2017. PMID: 28659468 Free PMC article.

10

Structural understanding of T cell receptor triggering.

Xu X, Li H, Xu C. Xu X, et al. Among authors: xu c. Cell Mol Immunol. 2020 Mar;17(3):193-202. doi: 10.1038/s41423-020-0367-1. Epub 2020 Feb 11. Cell Mol Immunol. 2020. PMID: 32047259 Free PMC article. Review.

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