Xiong Y - Search Results

1

Inhibition of USP7 induces p53-independent tumor growth suppression in triple-negative breast cancers by destabilizing FOXM1.

Yi J, Li H, Chu B, Kon N, Hu X, Hu J, Xiong Y, Kaniskan HU, Jin J, Gu W. Yi J, et al. Among authors: xiong y. Cell Death Differ. 2023 Jul;30(7):1799-1810. doi: 10.1038/s41418-023-01180-7. Epub 2023 Jun 8. Cell Death Differ. 2023. PMID: 37291217

2

Structure-activity relationship studies of SETD8 inhibitors.

Ma A, Yu W, Xiong Y, Butler KV, Brown PJ, Jin J. Ma A, et al. Among authors: xiong y. Medchemcomm. 2014 Dec;5(12):1892-1898. doi: 10.1039/C4MD00317A. Medchemcomm. 2014. PMID: 25554733 Free PMC article.

3

Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.

Wagner T, Greschik H, Burgahn T, Schmidtkunz K, Schott AK, McMillan J, Baranauskienė L, Xiong Y, Fedorov O, Jin J, Oppermann U, Matulis D, Schüle R, Jung M. Wagner T, et al. Among authors: xiong y. Nucleic Acids Res. 2016 May 19;44(9):e88. doi: 10.1093/nar/gkw089. Epub 2016 Feb 17. Nucleic Acids Res. 2016. PMID: 26893353 Free PMC article.

4

Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome.

Kim Y, Lee HM, Xiong Y, Sciaky N, Hulbert SW, Cao X, Everitt JI, Jin J, Roth BL, Jiang YH. Kim Y, et al. Among authors: xiong y. Nat Med. 2017 Feb;23(2):213-222. doi: 10.1038/nm.4257. Epub 2016 Dec 26. Nat Med. 2017. PMID: 28024084 Free PMC article.

5

Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.

Xiong Y, Li F, Babault N, Dong A, Zeng H, Wu H, Chen X, Arrowsmith CH, Brown PJ, Liu J, Vedadi M, Jin J. Xiong Y, et al. J Med Chem. 2017 Mar 9;60(5):1876-1891. doi: 10.1021/acs.jmedchem.6b01645. Epub 2017 Feb 14. J Med Chem. 2017. PMID: 28135087 Free PMC article.

6

Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.

Xiong Y, Li F, Babault N, Wu H, Dong A, Zeng H, Chen X, Arrowsmith CH, Brown PJ, Liu J, Vedadi M, Jin J. Xiong Y, et al. Bioorg Med Chem. 2017 Aug 15;25(16):4414-4423. doi: 10.1016/j.bmc.2017.06.021. Epub 2017 Jun 19. Bioorg Med Chem. 2017. PMID: 28662962 Free PMC article.

7

Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.

Wang DY, Kosowan J, Samsom J, Leung L, Zhang KL, Li YX, Xiong Y, Jin J, Petronis A, Oh G, Wong AHC. Wang DY, et al. Among authors: xiong y. Acta Pharmacol Sin. 2018 May;39(5):866-874. doi: 10.1038/aps.2017.190. Epub 2018 Feb 8. Acta Pharmacol Sin. 2018. PMID: 29417943 Free PMC article.

8

A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques.

Allen DC, Carlson TL, Xiong Y, Jin J, Grant KA, Cuzon Carlson VC. Allen DC, et al. Among authors: xiong y. J Pharmacol Exp Ther. 2019 Feb;368(2):199-207. doi: 10.1124/jpet.118.252031. Epub 2018 Dec 6. J Pharmacol Exp Ther. 2019. PMID: 30523062 Free PMC article.

9

Multi-omic Dissection of Oncogenically Active Epiproteomes Identifies Drivers of Proliferative and Invasive Breast Tumors.

Wrobel JA, Xie L, Wang L, Liu C, Rashid N, Gallagher KK, Xiong Y, Konze KD, Jin J, Gatza ML, Chen X. Wrobel JA, et al. Among authors: xiong y. iScience. 2019 Jul 26;17:359-378. doi: 10.1016/j.isci.2019.07.001. Epub 2019 Jul 4. iScience. 2019. PMID: 31336272 Free PMC article.

10

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

Fagan V, Johansson C, Gileadi C, Monteiro O, Dunford JE, Nibhani R, Philpott M, Malzahn J, Wells G, Faram R, Cribbs AP, Halidi N, Li F, Chau I, Greschik H, Velupillai S, Allali-Hassani A, Bennett J, Christott T, Giroud C, Lewis AM, Huber KVM, Athanasou N, Bountra C, Jung M, Schüle R, Vedadi M, Arrowsmith C, Xiong Y, Jin J, Fedorov O, Farnie G, Brennan PE, Oppermann U. Fagan V, et al. Among authors: xiong y. J Med Chem. 2019 Oct 24;62(20):9008-9025. doi: 10.1021/acs.jmedchem.9b00562. Epub 2019 Oct 15. J Med Chem. 2019. PMID: 31550156

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