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Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection.
Zhang W, Lyu M, Bessman NJ, Xie Z, Arifuzzaman M, Yano H, Parkhurst CN, Chu C, Zhou L, Putzel GG, Li TT, Jin WB, Zhou J; JRI Live Cell Bank; Hu H, Tsou AM, Guo CJ, Artis D. Zhang W, et al. Among authors: xie z. Cell. 2022 Oct 27;185(22):4170-4189.e20. doi: 10.1016/j.cell.2022.09.008. Epub 2022 Oct 14. Cell. 2022. PMID: 36240781 Free PMC article.
TRP Channels as Drug Targets to Relieve Itch.
Xie Z, Hu H. Xie Z, et al. Pharmaceuticals (Basel). 2018 Oct 6;11(4):100. doi: 10.3390/ph11040100. Pharmaceuticals (Basel). 2018. PMID: 30301231 Free PMC article. Review.
A basophil-neuronal axis promotes itch.
Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS. Wang F, et al. Among authors: xie z. Cell. 2021 Jan 21;184(2):422-440.e17. doi: 10.1016/j.cell.2020.12.033. Epub 2021 Jan 14. Cell. 2021. PMID: 33450207 Free PMC article.
Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice.
Cao L, Yue X, Zhao Y, Du L, Xie Z, Yuan Y, Zhang S, Li F, Feng J, Hu H. Cao L, et al. Among authors: xie z. J Invest Dermatol. 2021 Oct;141(10):2499-2508.e3. doi: 10.1016/j.jid.2021.03.015. Epub 2021 Apr 1. J Invest Dermatol. 2021. PMID: 33812858 Free PMC article.
Mechanosensitive TRPV4 is required for crystal-induced inflammation.
Lan Z, Chen L, Feng J, Xie Z, Liu Z, Wang F, Liu P, Yue X, Du L, Zhao Y, Yang P, Luo J, Zhu Z, Hu X, Cao L, Lu P, Sah R, Lavine K, Kim B, Hu H. Lan Z, et al. Among authors: xie z. Ann Rheum Dis. 2021 Dec;80(12):1604-1614. doi: 10.1136/annrheumdis-2021-220295. Epub 2021 Oct 18. Ann Rheum Dis. 2021. PMID: 34663597 Free PMC article.
Ion channel regulation of gut immunity.
Feng J, Xie Z, Hu H. Feng J, et al. Among authors: xie z. J Gen Physiol. 2023 Feb 6;155(2):e202113042. doi: 10.1085/jgp.202113042. Epub 2022 Dec 2. J Gen Physiol. 2023. PMID: 36459135 Free PMC article.
A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain.
Hu X, Du L, Liu S, Lan Z, Zang K, Feng J, Zhao Y, Yang X, Xie Z, Wang PL, Ver Heul AM, Chen L, Samineni VK, Wang YQ, Lavine KJ, Gereau RW 4th, Wu GF, Hu H. Hu X, et al. Among authors: xie z. J Clin Invest. 2023 Mar 1;133(5):e161507. doi: 10.1172/JCI161507. J Clin Invest. 2023. PMID: 36701202 Free PMC article.
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