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Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X, Cheng Z, Li L, Xie Y, Liu Z, Fang W. Liu Y, et al. EBioMedicine. 2019 Oct;48:386-404. doi: 10.1016/j.ebiom.2019.08.040. Epub 2019 Oct 5. EBioMedicine. 2019. PMID: 31594754 Free PMC article.
The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc deubiquitination in lung adenocarcinoma.
Liu JH, Yang HL, Deng ST, Hu Z, Chen WF, Yan WW, Hou RT, Li YH, Xian RT, Xie YY, Su Y, Wu LY, Xu P, Zhu ZB, Liu X, Deng YL, Wang YB, Liu Z, Fang WY. Liu JH, et al. Among authors: xie yy. Acta Pharmacol Sin. 2022 Oct;43(10):2687-2695. doi: 10.1038/s41401-022-00890-x. Epub 2022 Mar 16. Acta Pharmacol Sin. 2022. PMID: 35296779 Free PMC article.
338 results