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Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine.
Tan YS, Sansanaphongpricha K, Xie Y, Donnelly CR, Luo X, Heath BR, Zhao X, Bellile E, Hu H, Chen H, Polverini PJ, Chen Q, Young S, Carey TE, Nör JE, Ferris RL, Wolf GT, Sun D, Lei YL. Tan YS, et al. Among authors: xie y. Clin Cancer Res. 2018 Sep 1;24(17):4242-4255. doi: 10.1158/1078-0432.CCR-17-2807. Epub 2018 May 16. Clin Cancer Res. 2018. PMID: 29769207 Free PMC article.
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.
Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL. Luo X, et al. Among authors: xie y. J Clin Invest. 2020 Apr 1;130(4):1635-1652. doi: 10.1172/JCI129497. J Clin Invest. 2020. PMID: 31874109 Free PMC article.
OXPHOS promotes apoptotic resistance and cellular persistence in TH17 cells in the periphery and tumor microenvironment.
Hong HS, Mbah NE, Shan M, Loesel K, Lin L, Sajjakulnukit P, Correa LO, Andren A, Lin J, Hayashi A, Magnuson B, Chen J, Li Z, Xie Y, Zhang L, Goldstein DR, Carty SA, Lei YL, Opipari AW, Argüello RJ, Kryczek I, Kamada N, Zou W, Franchi L, Lyssiotis CA. Hong HS, et al. Among authors: xie y. Sci Immunol. 2022 Nov 25;7(77):eabm8182. doi: 10.1126/sciimmunol.abm8182. Epub 2022 Nov 18. Sci Immunol. 2022. PMID: 36399539 Free PMC article.
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