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Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X, Cheng Z, Li L, Xie Y, Liu Z, Fang W. Liu Y, et al. Among authors: xie y. EBioMedicine. 2019 Oct;48:386-404. doi: 10.1016/j.ebiom.2019.08.040. Epub 2019 Oct 5. EBioMedicine. 2019. PMID: 31594754 Free PMC article.
NAP1L1 promotes proliferation and chemoresistance in glioma by inducing CCND1/CDK4/CDK6 expression through its interaction with HDGF and activation of c-Jun.
Chen Z, Xie Y, Luo H, Song Y, Que T, Hu R, Huang H, Luo K, Li C, Qin C, Zheng C, Fang W, Liu L, Long H, Luo Q. Chen Z, et al. Among authors: xie y. Aging (Albany NY). 2021 Dec 27;13(24):26180-26200. doi: 10.18632/aging.203805. Epub 2021 Dec 27. Aging (Albany NY). 2021. PMID: 34959221 Free PMC article.
The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc deubiquitination in lung adenocarcinoma.
Liu JH, Yang HL, Deng ST, Hu Z, Chen WF, Yan WW, Hou RT, Li YH, Xian RT, Xie YY, Su Y, Wu LY, Xu P, Zhu ZB, Liu X, Deng YL, Wang YB, Liu Z, Fang WY. Liu JH, et al. Among authors: xie yy. Acta Pharmacol Sin. 2022 Oct;43(10):2687-2695. doi: 10.1038/s41401-022-00890-x. Epub 2022 Mar 16. Acta Pharmacol Sin. 2022. PMID: 35296779 Free PMC article.
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
Zhang Z, Xu P, Hu Z, Fu Z, Deng T, Deng X, Peng L, Xie Y, Long L, Zheng D, Shen P, Zhang M, Gong B, Zhu Z, Lin J, Chen R, Liu Z, Yang H, Li R, Fang W. Zhang Z, et al. Among authors: xie y. Int J Biol Sci. 2022 Jun 27;18(10):4171-4186. doi: 10.7150/ijbs.69332. eCollection 2022. Int J Biol Sci. 2022. PMID: 35844805 Free PMC article.
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