Xie X - Search Results

1

Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 1: Tuning the N-substituents.

Ben L, Jones ED, Zhou E, Li C, Baylis DC, Yu S, Wang M, He X, Coates JA, Rhodes DI, Pei G, Deadman JJ, Xie X, Ma D. Ben L, et al. Among authors: xie x. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4012-4. doi: 10.1016/j.bmcl.2010.05.102. Epub 2010 Jun 1. Bioorg Med Chem Lett. 2010. PMID: 20561788

2

Small molecule regulators of autophagy identified by an image-based high-throughput screen.

Zhang L, Yu J, Pan H, Hu P, Hao Y, Cai W, Zhu H, Yu AD, Xie X, Ma D, Yuan J. Zhang L, et al. Among authors: xie x. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19023-8. doi: 10.1073/pnas.0709695104. Epub 2007 Nov 16. Proc Natl Acad Sci U S A. 2007. PMID: 18024584 Free PMC article.

3

Discovery of a novel CCR5 antagonist lead compound through fragment assembly.

Liu Y, Zhou E, Yu K, Zhu J, Zhang Y, Xie X, Li J, Jiang H. Liu Y, et al. Among authors: xie x. Molecules. 2008 Oct 1;13(10):2426-41. doi: 10.3390/molecules13102426. Molecules. 2008. PMID: 18830165 Free PMC article.

4

Bryostatin-5 blocks stromal cell-derived factor-1 induced chemotaxis via desensitization and down-regulation of cell surface CXCR4 receptors.

He X, Fang L, Wang J, Yi Y, Zhang S, Xie X. He X, et al. Among authors: xie x. Cancer Res. 2008 Nov 1;68(21):8678-86. doi: 10.1158/0008-5472.CAN-08-0294. Cancer Res. 2008. PMID: 18974109

5

Synthesis and opioid receptor activity of indolopropellanes.

Li F, Gaob L, Yin C, Chen J, Liu J, Xie X, Zhang A. Li F, et al. Among authors: xie x. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4603-6. doi: 10.1016/j.bmcl.2009.06.093. Epub 2009 Jun 30. Bioorg Med Chem Lett. 2009. PMID: 19595591

6

Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.

Meng T, Wang J, Peng H, Fang G, Li M, Xiong B, Xie X, Zhang Y, Wang X, Shen J. Meng T, et al. Among authors: xie x. Eur J Med Chem. 2010 Mar;45(3):1133-9. doi: 10.1016/j.ejmech.2009.12.018. Epub 2009 Dec 16. Eur J Med Chem. 2010. PMID: 20047779

7

Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents.

Li B, Jones ED, Zhou E, Chen L, Baylis DC, Yu S, Wang M, He X, Coates JA, Rhodes DI, Pei G, Deadman JJ, Xie X, Ma D. Li B, et al. Among authors: xie x. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5334-6. doi: 10.1016/j.bmcl.2010.05.046. Epub 2010 May 19. Bioorg Med Chem Lett. 2010. PMID: 20674358

8

Structural optimization and biological evaluation of substituted bisphenol A derivatives as beta-amyloid peptide aggregation inhibitors.

Zhou Y, Jiang C, Zhang Y, Liang Z, Liu W, Wang L, Luo C, Zhong T, Sun Y, Zhao L, Xie X, Jiang H, Zhou N, Liu D, Liu H. Zhou Y, et al. Among authors: xie x. J Med Chem. 2010 Aug 12;53(15):5449-66. doi: 10.1021/jm1000584. J Med Chem. 2010. PMID: 20684593

9

Asymmetric synthesis and biological evaluation of N-cyclohexyl-4-[1-(2,4-dichlorophenyl)-1-(p-tolyl)methyl]piperazine-1-carboxamide as hCB1 receptor antagonists.

Gao L, Li M, Meng T, Peng H, Xie X, Zhang Y, Jin Y, Wang X, Zou L, Shen J. Gao L, et al. Among authors: xie x. Eur J Med Chem. 2011 Nov;46(11):5310-6. doi: 10.1016/j.ejmech.2011.08.030. Epub 2011 Sep 1. Eur J Med Chem. 2011. PMID: 21937154

10

Design, synthesis, and biological evaluation of novel piperidine-4-carboxamide derivatives as potent CCR5 inhibitors.

Hu S, Gu Q, Wang Z, Weng Z, Cai Y, Dong X, Hu Y, Liu T, Xie X. Hu S, et al. Among authors: xie x. Eur J Med Chem. 2014 Jan;71:259-66. doi: 10.1016/j.ejmech.2013.11.013. Epub 2013 Nov 19. Eur J Med Chem. 2014. PMID: 24316669

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