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Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells.
Nguyenla X, Wehri E, Van Dis E, Biering SB, Yamashiro LH, Zhu C, Stroumza J, Dugast-Darzacq C, Graham TGW, Wang X, Jockusch S, Tao C, Chien M, Xie W, Patel DJ, Meyer C, Garzia A, Tuschl T, Russo JJ, Ju J, Näär AM, Stanley S, Schaletzky J. Nguyenla X, et al. Among authors: xie w. Sci Rep. 2022 Nov 2;12(1):18506. doi: 10.1038/s41598-022-21034-5. Sci Rep. 2022. PMID: 36323770 Free PMC article.
TRF2 binds branched DNA to safeguard telomere integrity.
Schmutz I, Timashev L, Xie W, Patel DJ, de Lange T. Schmutz I, et al. Among authors: xie w. Nat Struct Mol Biol. 2017 Sep;24(9):734-742. doi: 10.1038/nsmb.3451. Epub 2017 Aug 14. Nat Struct Mol Biol. 2017. PMID: 28805810
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T. Lama L, et al. Among authors: xie w. Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4. Nat Commun. 2019. PMID: 31113940 Free PMC article.
Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Xie W, Sowemimo I, Hayashi R, Wang J, Burkard TR, Brennecke J, Ameres SL, Patel DJ. Xie W, et al. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30370-30379. doi: 10.1073/pnas.2018156117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199607 Free PMC article.
The Card1 nuclease provides defence during type III CRISPR immunity.
Rostøl JT, Xie W, Kuryavyi V, Maguin P, Kao K, Froom R, Patel DJ, Marraffini LA. Rostøl JT, et al. Among authors: xie w. Nature. 2021 Feb;590(7847):624-629. doi: 10.1038/s41586-021-03206-x. Epub 2021 Jan 18. Nature. 2021. PMID: 33461211 Free PMC article.
DNA-driven condensation assembles the meiotic DNA break machinery.
Claeys Bouuaert C, Pu S, Wang J, Oger C, Daccache D, Xie W, Patel DJ, Keeney S. Claeys Bouuaert C, et al. Among authors: xie w. Nature. 2021 Apr;592(7852):144-149. doi: 10.1038/s41586-021-03374-w. Epub 2021 Mar 17. Nature. 2021. PMID: 33731927 Free PMC article.
8,939 results