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Genetic and pharmacological inhibition of GRPR protects against acute kidney injury via attenuating renal inflammation and necroptosis.
Li C, Ma QY, Liu XQ, Li HD, Yu MJ, Xie SS, Ma WX, Chen Y, Wang JN, He RB, Bian HG, He Y, Gao L, Deng SS, Zang HM, Gong Q, Wen JG, Liu MM, Yang C, Chen HY, Li J, Lan HY, Jin J, Yao RS, Meng XM. Li C, et al. Among authors: xie ss. Mol Ther. 2023 Sep 6;31(9):2734-2754. doi: 10.1016/j.ymthe.2023.06.016. Epub 2023 Jul 5. Mol Ther. 2023. PMID: 37415332
Insulin-like growth factor binding protein 7 promotes acute kidney injury by alleviating poly ADP ribose polymerase 1 degradation.
Yu JT, Hu XW, Yang Q, Shan RR, Zhang Y, Dong ZH, Li HD, Wang JN, Li C, Xie SS, Dong YH, Ni WJ, Jiang L, Liu XQ, Wei B, Wen JG, Liu MM, Chen Q, Yang YR, Zhang GY, Zang HM, Jin J, Wu YG, Zhong X, Li J, Wang W, Meng XM. Yu JT, et al. Among authors: xie ss. Kidney Int. 2022 Oct;102(4):828-844. doi: 10.1016/j.kint.2022.05.026. Epub 2022 Jun 23. Kidney Int. 2022. PMID: 35752325
Cpd-0225 attenuates renal fibrosis via inhibiting ALK5.
Xie SS, Dong ZH, He Y, Chen ZW, Yang Q, Ma WX, Li C, Chen Y, Wang JN, Yu JT, Xu CH, Ni WJ, Hou R, Suo XG, Wen JG, Jin J, Li J, Liu MM, Meng XM. Xie SS, et al. Biochem Pharmacol. 2022 Oct;204:115240. doi: 10.1016/j.bcp.2022.115240. Epub 2022 Sep 5. Biochem Pharmacol. 2022. PMID: 36070847
Cpd-A1 alleviates acute kidney injury by inhibiting ferroptosis.
Chen Y, Wu MF, Xie MM, Lu Y, Li C, Xie SS, Ma WX, Ji ML, Hou R, Dong ZH, He RB, Zhang MM, Lu H, Gao L, Wen JG, Jin J, Dong XW, Che JX, Meng XM. Chen Y, et al. Among authors: xie ss. Acta Pharmacol Sin. 2024 Apr 19. doi: 10.1038/s41401-024-01277-w. Online ahead of print. Acta Pharmacol Sin. 2024. PMID: 38641746
251 results