Xie Q - Search Results

1

Adenosine A_2A Receptor Antagonists for Cancer Immunotherapy.

Yu F, Zhu C, Xie Q, Wang Y. Yu F, et al. Among authors: xie q. J Med Chem. 2020 Nov 12;63(21):12196-12212. doi: 10.1021/acs.jmedchem.0c00237. Epub 2020 Jul 30. J Med Chem. 2020. PMID: 32667814 Review.

2

QSAR study of 4-phenylpiperidine derivatives as mu opioid agonists by neural network method.

Wang XH, Tang Y, Xie Q, Qiu ZB. Wang XH, et al. Among authors: xie q. Eur J Med Chem. 2006 Feb;41(2):226-32. doi: 10.1016/j.ejmech.2005.10.017. Epub 2006 Jan 5. Eur J Med Chem. 2006. PMID: 16403590

3

Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.

Xie Q, Wang H, Xia Z, Lu M, Zhang W, Wang X, Fu W, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu Z, Chen H. Xie Q, et al. J Med Chem. 2008 Apr 10;51(7):2027-36. doi: 10.1021/jm070154q. Epub 2008 Mar 12. J Med Chem. 2008. PMID: 18333606

4

(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer's therapy.

Cheng S, Zheng W, Gong P, Zhou Q, Xie Q, Yu L, Zhang P, Chen L, Li J, Chen J, Chen H, Chen H. Cheng S, et al. Among authors: xie q. Bioorg Med Chem. 2015 Jul 1;23(13):3110-8. doi: 10.1016/j.bmc.2015.04.084. Epub 2015 May 12. Bioorg Med Chem. 2015. PMID: 26025073

5

Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine derivatives as acetylcholine-binding protein ligands.

Shen J, Yang XC, Yu MC, Xiao L, Zhang XJ, Sun HJ, Chen H, Pan GX, Yan YR, Wang SC, Li W, Zhou L, Xie Q, Yu LQ, Wang YH, Shao LM. Shen J, et al. Among authors: xie q. Acta Pharmacol Sin. 2017 Jan;38(1):146-155. doi: 10.1038/aps.2016.124. Epub 2016 Dec 5. Acta Pharmacol Sin. 2017. PMID: 27917874 Free PMC article.

6

The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent κ-Opioid Agonistic Activities.

Li W, Long JD, Qian YY, Long Y, Xu XJ, Wang YJ, Shen Q, Wang ZN, Yang XC, Xiao L, Sun HP, Xu YL, Chen YY, Xie Q, Wang YH, Shao LM, Liu JG, Qiu ZB, Fu W. Li W, et al. Among authors: xie q. ACS Chem Neurosci. 2017 Apr 19;8(4):766-776. doi: 10.1021/acschemneuro.6b00321. Epub 2017 Jan 19. ACS Chem Neurosci. 2017. PMID: 28033462

7

Pharmacophore-based design and discovery of (-)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis.

Xie Q, Zheng Z, Shao B, Fu W, Xia Z, Li W, Sun J, Zheng W, Zhang W, Sheng W, Zhang Q, Chen H, Wang H, Qiu Z. Xie Q, et al. J Enzyme Inhib Med Chem. 2017 Dec;32(1):659-671. doi: 10.1080/14756366.2016.1265521. J Enzyme Inhib Med Chem. 2017. PMID: 28274151 Free PMC article.

8

Discovery of carbazole carboxamides as novel RORγt inverse agonists.

Huang Y, Yu M, Sun N, Tang T, Yu F, Song X, Xie Q, Fu W, Shao L, Wang Y. Huang Y, et al. Among authors: xie q. Eur J Med Chem. 2018 Mar 25;148:465-476. doi: 10.1016/j.ejmech.2018.02.050. Epub 2018 Feb 16. Eur J Med Chem. 2018. PMID: 29477887

9

Discovery of novel 20S proteasome inhibitors by rational topology-based scaffold hopping of bortezomib.

Xu Y, Yang X, Chen Y, Chen H, Sun H, Li W, Xie Q, Yu L, Shao L. Xu Y, et al. Among authors: xie q. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2148-2152. doi: 10.1016/j.bmcl.2018.05.018. Epub 2018 May 9. Bioorg Med Chem Lett. 2018. PMID: 29773504

10

7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues.

Sun HJ, Wang YH, Yuan CM, Kong LH, Xu XJ, Wang YJ, Wu HH, Lin C, Qian YY, Huang HM, Xiao L, Liu X, He Q, Fang SY, Xue DQ, Yang XC, Chen H, Zheng YL, Zheng L, Yu LQ, Xie Q, Fu W, Li W, Liu JG, Qiu ZB, Shao LM. Sun HJ, et al. Among authors: xie q. Bioorg Med Chem. 2018 Aug 7;26(14):4254-4263. doi: 10.1016/j.bmc.2018.07.020. Epub 2018 Jul 24. Bioorg Med Chem. 2018. PMID: 30054192

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