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Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis.
Liu Y, Peng J, Sun T, Li N, Zhang L, Ren J, Yuan H, Kan S, Pan Q, Li X, Ding Y, Jiang M, Cong X, Tan M, Ma Y, Fu D, Cai S, Xiao Y, Wang X, Qin J. Liu Y, et al. Among authors: xiao y. Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3796-E3805. doi: 10.1073/pnas.1700909114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28439030 Free PMC article.
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24.
Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, Chen X, Hou D, Wang Y, Pan Q, Xu J, Zhang X, Liu J, Pei S, Peng C, Wu P, Romano S, Mao C, Huang M, Zhu X, Shen K, Qin J, Xiao Y. Yu T, et al. Among authors: xiao y. Nat Commun. 2019 Sep 25;10(1):4353. doi: 10.1038/s41467-019-12384-2. Nat Commun. 2019. PMID: 31554795 Free PMC article.
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Huang X, Hao S, Liu J, Huang Y, Liu M, Xiao C, Wang Y, Pei S, Yu T, Xu J, Wang H, Dai D, Su X, Xiao Y. Huang X, et al. Among authors: xiao y, xiao c. Cell Mol Immunol. 2021 Apr;18(4):969-978. doi: 10.1038/s41423-021-00660-5. Epub 2021 Mar 11. Cell Mol Immunol. 2021. PMID: 33707688 Free PMC article.
BFAR coordinates TGFβ signaling to modulate Th9-mediated cancer immunotherapy.
Pei S, Huang M, Huang J, Zhu X, Wang H, Romano S, Deng X, Wang Y, Luo Y, Hao S, Xu J, Yu T, Zhu Q, Yuan J, Shen K, Liu Z, Hu G, Peng C, Luo Q, Wen Z, Dai D, Xiao Y. Pei S, et al. Among authors: xiao y. J Exp Med. 2021 Jul 5;218(7):e20202144. doi: 10.1084/jem.20202144. J Exp Med. 2021. PMID: 33914044 Free PMC article.
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