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Safety and activity of an engineered, liver-tropic adeno-associated virus vector expressing a hyperactive Padua factor IX administered with prophylactic glucocorticoids in patients with haemophilia B: a single-centre, single-arm, phase 1, pilot trial.
Xue F, Li H, Wu X, Liu W, Zhang F, Tang D, Chen Y, Wang W, Chi Y, Zheng J, Du Z, Jiang W, Zhong C, Wei J, Zhu P, Fu R, Liu X, Chen L, Pei X, Sun J, Cheng T, Yang R, Xiao X, Zhang L. Xue F, et al. Among authors: xiao x. Lancet Haematol. 2022 Jul;9(7):e504-e513. doi: 10.1016/S2352-3026(22)00113-2. Epub 2022 May 19. Lancet Haematol. 2022. PMID: 35598604 Clinical Trial.
Directed evolution of adeno-associated virus 5 capsid enables specific liver tropism.
Wang Y, Yang C, Hu H, Chen C, Yan M, Ling F, Wang KC, Wang X, Deng Z, Zhou X, Zhang F, Lin S, Du Z, Zhao K, Xiao X. Wang Y, et al. Among authors: xiao x. Mol Ther Nucleic Acids. 2022 Mar 21;28:293-306. doi: 10.1016/j.omtn.2022.03.017. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35474733 Free PMC article.
[Study on the Therapeutic Effect of Lenalidomide on Hemophilic Arthropathy].
Wang YF, Lin ZY, Zhang FX, Zhou XY, Wu X, Xiao X, Sun JJ, Hua BL. Wang YF, et al. Among authors: xiao x. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2022 Oct;30(5):1549-1556. doi: 10.19746/j.cnki.issn.1009-2137.2022.05.038. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2022. PMID: 36208264 Chinese.
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