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RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer.
Deng P, Wang Z, Chen J, Liu S, Yao X, Liu S, Liu L, Yu Z, Huang Y, Xiong Z, Xiao R, Gao J, Liang W, Chen J, Liu H, Hong JH, Chan JY, Guan P, Chen J, Wang Y, Yin J, Li J, Zheng M, Zhang C, Zhou P, Kang T, Teh BT, Yu Q, Zuo Z, Jiang Q, Liu J, Xiong Y, Xia X, Tan J. Deng P, et al. Among authors: xiao r. J Clin Invest. 2022 Nov 15;132(22):e159628. doi: 10.1172/JCI159628. J Clin Invest. 2022. PMID: 36201246 Free PMC article.
Targeting enhancer reprogramming to mitigate MEK inhibitor resistance in preclinical models of advanced ovarian cancer.
Liu S, Zou Q, Chen JP, Yao X, Guan P, Liang W, Deng P, Lai X, Yin J, Chen J, Chen R, Yu Z, Xiao R, Sun Y, Hong JH, Liu H, Lu H, Chen J, Bei JX, Koh J, Chan JY, Wang B, Kang T, Yu Q, Teh BT, Liu J, Xiong Y, Tan J. Liu S, et al. Among authors: xiao r. J Clin Invest. 2021 Oct 15;131(20):e145035. doi: 10.1172/JCI145035. J Clin Invest. 2021. PMID: 34464356 Free PMC article.
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies.
Hong JH, Yong CH, Heng HL, Chan JY, Lau MC, Chen J, Lee JY, Lim AH, Li Z, Guan P, Chu PL, Boot A, Ng SR, Yao X, Wee FYT, Lim JCT, Liu W, Wang P, Xiao R, Zeng X, Sun Y, Koh J, Kwek XY, Ng CCY, Klanrit P, Zhang Y, Lai J, Tai DWM, Pairojkul C, Dima S, Popescu I, Hsieh SY, Yu MC, Yeong J, Kongpetch S, Jusakul A, Loilome W, Tan P, Tan J, Teh BT. Hong JH, et al. Among authors: xiao r. Gut. 2024 May 10;73(6):966-984. doi: 10.1136/gutjnl-2023-330483. Gut. 2024. PMID: 38050079
Pharmacological modulation of RB1 activity mitigates resistance to neoadjuvant chemotherapy in locally advanced rectal cancer.
Yu Z, Deng P, Chen Y, Lin D, Liu S, Hong J, Guan P, Chen J, Zhong ME, Chen J, Chen X, Sun Y, Wang Y, Wang P, Cai Z, Chan JY, Huang Y, Xiao R, Guo Y, Zeng X, Wang W, Zou Y, Yu Q, Lan P, Teh BT, Wu X, Tan J. Yu Z, et al. Among authors: xiao r. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2304619121. doi: 10.1073/pnas.2304619121. Epub 2024 Jan 30. Proc Natl Acad Sci U S A. 2024. PMID: 38289962
3,076 results