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Structure, function and pharmacology of human itch receptor complexes.
Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, Li Z, Zhou J, Yu X, Gao N, Sun JP. Yang F, et al. Among authors: xiao p. Nature. 2021 Dec;600(7887):164-169. doi: 10.1038/s41586-021-04077-y. Epub 2021 Nov 17. Nature. 2021. PMID: 34789875
Structural basis of GPBAR activation and bile acid recognition.
Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, Ma C, Zhang K, Liang X, Shen Y, Nan F, Yi F, Luca VC, Zhou J, Jiang C, Sun JP, Xie X, Yu X, Zhang Y. Yang F, et al. Among authors: xiao p. Nature. 2020 Nov;587(7834):499-504. doi: 10.1038/s41586-020-2569-1. Epub 2020 Jul 22. Nature. 2020. PMID: 32698187
Structures of the glucocorticoid-bound adhesion receptor GPR97-Go complex.
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP. Ping YQ, et al. Among authors: xiao p. Nature. 2021 Jan;589(7843):620-626. doi: 10.1038/s41586-020-03083-w. Epub 2021 Jan 6. Nature. 2021. PMID: 33408414
Structural basis for the tethered peptide activation of adhesion GPCRs.
Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, Zhang DL, Zhu ZL, Jiang Y, Du L, Feng SQ, Schöneberg T, Liebscher I, Xu HE, Sun JP. Ping YQ, et al. Among authors: xiao p. Nature. 2022 Apr;604(7907):763-770. doi: 10.1038/s41586-022-04619-y. Epub 2022 Apr 13. Nature. 2022. PMID: 35418678
Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.
Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, Qu CX, Xiao P, Liu CY, Thomsen AR, Joseph Cahill T 3rd, Kahsai AW, Yi F, Xiao KH, Xue T, Zhou Z, Yu X, Sun JP. Liu CH, et al. Among authors: xiao p, xiao kh. Nat Commun. 2017 Feb 9;8:14335. doi: 10.1038/ncomms14335. Nat Commun. 2017. PMID: 28181498 Free PMC article.
Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin.
Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, Yi F, Ruan K, Shen YM, Yu X, Sun JP, Wang J. Yang F, et al. Among authors: xiao p. Nat Chem Biol. 2018 Sep;14(9):876-886. doi: 10.1038/s41589-018-0115-3. Epub 2018 Aug 17. Nat Chem Biol. 2018. PMID: 30120361
DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1H-NMR probe.
Liu Q, He QT, Lyu X, Yang F, Zhu ZL, Xiao P, Yang Z, Zhang F, Yang ZY, Wang XY, Sun P, Wang QW, Qu CX, Gong Z, Lin JY, Xu Z, Song SL, Huang SM, Guo SC, Han MJ, Zhu KK, Chen X, Kahsai AW, Xiao KH, Kong W, Li FH, Ruan K, Li ZJ, Yu X, Niu XG, Jin CW, Wang J, Sun JP. Liu Q, et al. Among authors: xiao p, xiao kh. Nat Commun. 2020 Sep 25;11(1):4857. doi: 10.1038/s41467-020-18433-5. Nat Commun. 2020. PMID: 32978402 Free PMC article.
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, He YH, Zhang DL, Zhang C, Hou GH, Liu H, Zhu L, Fu P, Yang S, Rosenbaum DM, Sun JP, Du Y, Zhang L, Yu X, Shao Z. Xiao P, et al. Cell. 2021 Feb 18;184(4):943-956.e18. doi: 10.1016/j.cell.2021.01.028. Epub 2021 Feb 10. Cell. 2021. PMID: 33571432 Free PMC article.
Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E2 receptor EP2 subtype.
Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, Zhang PJ, Hou G, Li Z, Yu X, Chai RJ, Guan YF, Sun JP, Zhang Y. Qu C, et al. Among authors: xiao p. Sci Adv. 2021 Apr 2;7(14):eabf1268. doi: 10.1126/sciadv.abf1268. Print 2021 Apr. Sci Adv. 2021. PMID: 33811074 Free PMC article.
2,464 results