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The extent of liver injury determines hepatocyte fate toward senescence or cancer.
Wang C, Chen WJ, Wu YF, You P, Zheng SY, Liu CC, Xiang D, Wang MJ, Cai YC, Zhao QH, Borjigin U, Liu W, Xiong WJ, Wangensteen KJ, Wang X, Liu ZM, He ZY. Wang C, et al. Among authors: xiang d. Cell Death Dis. 2018 May 1;9(5):575. doi: 10.1038/s41419-018-0622-x. Cell Death Dis. 2018. PMID: 29760381 Free PMC article.
Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation.
Xiang D, Liu CC, Wang MJ, Li JX, Chen F, Yao H, Yu B, Lu L, Borjigin U, Chen YX, Zhong L, Wangensteen KJ, He ZY, Wang X, Hu YP. Xiang D, et al. Cell Death Dis. 2014 May 22;5(5):e1252. doi: 10.1038/cddis.2014.230. Cell Death Dis. 2014. PMID: 24853430 Free PMC article.
Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors.
Yu B, He ZY, You P, Han QW, Xiang D, Chen F, Wang MJ, Liu CC, Lin XW, Borjigin U, Zi XY, Li JX, Zhu HY, Li WL, Han CS, Wangensteen KJ, Shi Y, Hui LJ, Wang X, Hu YP. Yu B, et al. Among authors: xiang d. Cell Stem Cell. 2013 Sep 5;13(3):328-40. doi: 10.1016/j.stem.2013.06.017. Epub 2013 Jul 18. Cell Stem Cell. 2013. PMID: 23871605 Free article.
Reversal of hepatocyte senescence after continuous in vivo cell proliferation.
Wang MJ, Chen F, Li JX, Liu CC, Zhang HB, Xia Y, Yu B, You P, Xiang D, Lu L, Yao H, Borjigin U, Yang GS, Wangensteen KJ, He ZY, Wang X, Hu YP. Wang MJ, et al. Among authors: xiang d. Hepatology. 2014 Jul;60(1):349-61. doi: 10.1002/hep.27094. Epub 2014 May 28. Hepatology. 2014. PMID: 24711261
Xeno-repopulation of Fah -/- Nod/Scid mice livers by human hepatocytes.
Su B, Liu C, Xiang D, Zhang H, Yuan S, Wang M, Chen F, Zhu H, He Z, Wang X, Hu Y. Su B, et al. Among authors: xiang d. Sci China Life Sci. 2011 Mar;54(3):227-34. doi: 10.1007/s11427-011-4140-7. Epub 2011 Mar 16. Sci China Life Sci. 2011. PMID: 21416322 Free article.
Hepatic PHD2/HIF-1α axis is involved in postexercise systemic energy homeostasis.
Luo B, Xiang D, Wu D, Liu C, Fang Y, Chen P, Hu YP. Luo B, et al. Among authors: xiang d. FASEB J. 2018 Sep;32(9):4670-4680. doi: 10.1096/fj.201701139R. Epub 2018 Mar 30. FASEB J. 2018. PMID: 29601782
These findings also provide evidence that the hepatic PHD2/HIF-1alpha axis is involved in postexercise systemic metabolic homeostasis.-Luo, B., Xiang, D., Wu, D., Liu, C., Fang, Y., Chen, P., Hu, Y.-P. Hepatic PHD2/HIF-1alpha axis is involved in postexercise …
These findings also provide evidence that the hepatic PHD2/HIF-1alpha axis is involved in postexercise systemic metabolic homeostasis.-Luo, …
1,623 results