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Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors.
Yang JF, Xing X, Luo L, Zhou XW, Feng JX, Huang KB, Liu H, Jin S, Liu YN, Zhang SH, Pan YH, Yu B, Yang JY, Cao YL, Cao Y, Yang CY, Wang Y, Zhang Y, Li J, Xia X, Kang T, Xu RH, Lan P, Luo JH, Han H, Bai F, Gao S. Yang JF, et al. Among authors: xia x. Sci Immunol. 2023 Sep 29;8(87):eabq2424. doi: 10.1126/sciimmunol.abq2424. Epub 2023 Sep 22. Sci Immunol. 2023. PMID: 37738362
DGKA Mediates Resistance to PD-1 Blockade.
Fu L, Li S, Xiao W, Yu K, Li S, Yuan S, Shen J, Dong X, Fang Z, Zhang J, Chen S, Li W, You H, Xia X, Kang T, Tan J, Chen G, Yang AK, Gao Y, Zhou P. Fu L, et al. Among authors: xia x. Cancer Immunol Res. 2021 Apr;9(4):371-385. doi: 10.1158/2326-6066.CIR-20-0216. Epub 2021 Feb 19. Cancer Immunol Res. 2021. PMID: 33608256
Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy response.
He J, Xiong X, Yang H, Li D, Liu X, Li S, Liao S, Chen S, Wen X, Yu K, Fu L, Dong X, Zhu K, Xia X, Kang T, Bian C, Li X, Liu H, Ding P, Zhang X, Liu Z, Li W, Zuo Z, Zhou P. He J, et al. Among authors: xia x. Cell Res. 2022 Jun;32(6):530-542. doi: 10.1038/s41422-022-00627-9. Epub 2022 Feb 14. Cell Res. 2022. PMID: 35165422 Free PMC article.
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer.
Deng P, Wang Z, Chen J, Liu S, Yao X, Liu S, Liu L, Yu Z, Huang Y, Xiong Z, Xiao R, Gao J, Liang W, Chen J, Liu H, Hong JH, Chan JY, Guan P, Chen J, Wang Y, Yin J, Li J, Zheng M, Zhang C, Zhou P, Kang T, Teh BT, Yu Q, Zuo Z, Jiang Q, Liu J, Xiong Y, Xia X, Tan J. Deng P, et al. Among authors: xia x. J Clin Invest. 2022 Nov 15;132(22):e159628. doi: 10.1172/JCI159628. J Clin Invest. 2022. PMID: 36201246 Free PMC article.
CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia.
Wang J, Chen S, Xiao W, Li W, Wang L, Yang S, Wang W, Xu L, Liao S, Liu W, Wang Y, Liu N, Zhang J, Xia X, Kang T, Chen G, Cai X, Yang H, Zhang X, Lu Y, Zhou P. Wang J, et al. Among authors: xia x. J Hematol Oncol. 2018 Jan 10;11(1):7. doi: 10.1186/s13045-017-0553-5. J Hematol Oncol. 2018. PMID: 29316944 Free PMC article.
Smad4 Deficiency Promotes Pancreatic Cancer Immunogenicity by Activating the Cancer-Autonomous DNA-Sensing Signaling Axis.
Xiong W, He W, Wang T, He S, Xu F, Wang Z, Wang X, Guo H, Ling J, Zhang H, Liu Y, Xing K, Li M, Zhang H, Li J, Niu N, Xue J, Zhan Q, Liu ZX, Bei JX, Huang P, Liu J, Xia L, Xia X. Xiong W, et al. Among authors: xia l, xia x. Adv Sci (Weinh). 2022 Mar;9(7):e2103029. doi: 10.1002/advs.202103029. Epub 2022 Jan 22. Adv Sci (Weinh). 2022. PMID: 35064757 Free PMC article.
8,364 results