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Augmentation of Cystic Fibrosis Transmembrane Conductance Regulator Function in Human Bronchial Epithelial Cells via SLC6A14-Dependent Amino Acid Uptake. Implications for Treatment of Cystic Fibrosis.
Ahmadi S, Wu YS, Li M, Ip W, Lloyd-Kuzik A, Di Paola M, Du K, Xia S, Lew A, Bozoky Z, Forman-Kay J, Bear CE, Gonska T. Ahmadi S, et al. Among authors: xia s. Am J Respir Cell Mol Biol. 2019 Dec;61(6):755-764. doi: 10.1165/rcmb.2019-0094OC. Am J Respir Cell Mol Biol. 2019. PMID: 31189070
ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel.
Wu YS, Jiang J, Ahmadi S, Lew A, Laselva O, Xia S, Bartlett C, Ip W, Wellhauser L, Ouyang H, Gonska T, Moraes TJ, Bear CE. Wu YS, et al. Among authors: xia s. Mol Pharmacol. 2019 Oct;96(4):515-525. doi: 10.1124/mol.119.117143. Epub 2019 Aug 19. Mol Pharmacol. 2019. PMID: 31427400
A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients.
Jiang JX, Wellhauser L, Laselva O, Utkina I, Bozoky Z, Gunawardena T, Ngan Z, Xia S, Di Paola M, Eckford PDW, Ratjen F, Moraes TJ, Parkinson J, Wong AP, Bear CE. Jiang JX, et al. Among authors: xia s. Stem Cell Reports. 2021 Nov 9;16(11):2825-2837. doi: 10.1016/j.stemcr.2021.09.020. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678210 Free PMC article.
Conversion of human and mouse fibroblasts into lung-like epithelial cells.
Wong AP, Shojaie S, Liang Q, Xia S, Di Paola M, Ahmadi S, Bilodeau C, Garner J, Post M, Duchesneau P, Waddell TK, Bear CE, Nagy A, Rossant J. Wong AP, et al. Among authors: xia s. Sci Rep. 2019 Jun 21;9(1):9027. doi: 10.1038/s41598-019-45195-y. Sci Rep. 2019. PMID: 31227724 Free PMC article.
4,112 results