Xia H - Search Results

1

ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.

Wu Y, Zhang C, Liu X, He Z, Shan B, Zeng Q, Zhao Q, Zhu H, Liao H, Cen X, Xu X, Zhang M, Hou T, Wang Z, Yan H, Yang S, Sun Y, Chen Y, Wu R, Xie T, Chen W, Najafov A, Ying S, Xia H. Wu Y, et al. Among authors: xia h. Nat Commun. 2021 Apr 20;12(1):2346. doi: 10.1038/s41467-021-22467-8. Nat Commun. 2021. PMID: 33879767 Free PMC article.

2

G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L.

Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, Najafov A, Liu M, Li Y, Han X, Xiao J, Jin Z, Peng T, Gao Y, Cai Y, Qi C, Zhang Q, Sun A, Lipinski M, Zhu H, Xiong Y, Pandolfi PP, Li H, Yu Q, Yuan J. Zhang T, et al. Among authors: xia h. Elife. 2015 Mar 30;4:e06734. doi: 10.7554/eLife.06734. Elife. 2015. PMID: 25821988 Free PMC article.

3

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.

Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H. Xia HG, et al. J Cell Biol. 2015 Aug 31;210(5):705-16. doi: 10.1083/jcb.201503044. J Cell Biol. 2015. PMID: 26323688 Free PMC article.

4

C(sp²)-H functionalization of aldehyde-derived hydrazones via a radical process.

Xu X, Zhang J, Xia H, Wu J. Xu X, et al. Among authors: xia h. Org Biomol Chem. 2018 Feb 21;16(8):1227-1241. doi: 10.1039/c8ob00056e. Org Biomol Chem. 2018. PMID: 29431815 Review.

5

Drug Discovery Targeting Anaplastic Lymphoma Kinase (ALK).

Kong X, Pan P, Sun H, Xia H, Wang X, Li Y, Hou T. Kong X, et al. Among authors: xia h. J Med Chem. 2019 Dec 26;62(24):10927-10954. doi: 10.1021/acs.jmedchem.9b00446. Epub 2019 Aug 26. J Med Chem. 2019. PMID: 31419130 Review.

6

Bromo- and extraterminal domain protein inhibition improves immunotherapy efficacy in hepatocellular carcinoma.

Liu C, Miao X, Wang Y, Wen L, Cheng X, Kong D, Zhao P, Song D, Wang X, Ding X, Xia H, Wang W, Sun Q, Gong W. Liu C, et al. Among authors: xia h. Cancer Sci. 2020 Oct;111(10):3503-3515. doi: 10.1111/cas.14588. Epub 2020 Aug 17. Cancer Sci. 2020. PMID: 32726482 Free PMC article.

7

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.

Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q, Sun Q, Yi C, Wu J, Najafov A, Xia H. Cen X, et al. Among authors: xia h. Nat Commun. 2020 Nov 12;11(1):5731. doi: 10.1038/s41467-020-19547-6. Nat Commun. 2020. PMID: 33184293 Free PMC article.

8

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.

Najafov A, Luu HS, Mookhtiar AK, Mifflin L, Xia HG, Amin PP, Ordureau A, Wang H, Yuan J. Najafov A, et al. Among authors: xia hg. Mol Cell. 2021 Jan 21;81(2):370-385.e7. doi: 10.1016/j.molcel.2020.11.008. Epub 2020 Dec 2. Mol Cell. 2021. PMID: 33271062 Free article.

9

Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease.

Cen X, Xu X, Xia H. Cen X, et al. Among authors: xia h. Autophagy. 2021 Mar;17(3):818-819. doi: 10.1080/15548627.2020.1860542. Epub 2020 Dec 20. Autophagy. 2021. PMID: 33342330 Free PMC article.

10

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.

Xu X, Sun Y, Cen X, Shan B, Zhao Q, Xie T, Wang Z, Hou T, Xue Y, Zhang M, Peng D, Sun Q, Yi C, Najafov A, Xia H. Xu X, et al. Among authors: xia h. Protein Cell. 2021 Oct;12(10):769-787. doi: 10.1007/s13238-021-00858-3. Epub 2021 Jul 21. Protein Cell. 2021. PMID: 34291435 Free PMC article.

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