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Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Marei H, Tsai WK, Kee YS, Ruiz K, He J, Cox C, Sun T, Penikalapati S, Dwivedi P, Choi M, Kan D, Saenz-Lopez P, Dorighi K, Zhang P, Kschonsak YT, Kljavin N, Amin D, Kim I, Mancini AG, Nguyen T, Wang C, Janezic E, Doan A, Mai E, Xi H, Gu C, Heinlein M, Biehs B, Wu J, Lehoux I, Harris S, Comps-Agrar L, Seshasayee D, de Sauvage FJ, Grimmer M, Li J, Agard NJ, de Sousa E Melo F. Marei H, et al. Among authors: xi h. Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6. Epub 2022 Sep 21. Nature. 2022. PMID: 36131013 Free PMC article.
Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development.
Mai E, Chan J, Goon L, Ego BK, Bevers J, Wong T, Wong M, Corpuz R, Xi H, Wu J, Schneider K, Seshasayee D, Grimbaldeston M, Nakamura G, Indjeian VB, van Lookeren Campagne M, Loyet KM, Comps-Agrar L. Mai E, et al. Among authors: xi h. J Transl Med. 2021 Dec 20;19(1):517. doi: 10.1186/s12967-021-03189-3. J Transl Med. 2021. PMID: 34930320 Free PMC article.
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Liang WC, Xi H, Sun D, D'Ascenzo L, Zarzar J, Stephens N, Cook R, Li Y, Ye Z, Matsumoto M, Payandeh J, Masureel M, Wu Y. Liang WC, et al. Among authors: xi h. MAbs. 2024 Jan-Dec;16(1):2309685. doi: 10.1080/19420862.2024.2309685. Epub 2024 Feb 14. MAbs. 2024. PMID: 38356181 Free PMC article.
IL-33 amplifies an innate immune response in the degenerating retina.
Xi H, Katschke KJ Jr, Li Y, Truong T, Lee WP, Diehl L, Rangell L, Tao J, Arceo R, Eastham-Anderson J, Hackney JA, Iglesias A, Cote-Sierra J, Elstrott J, Weimer RM, van Lookeren Campagne M. Xi H, et al. J Exp Med. 2016 Feb 8;213(2):189-207. doi: 10.1084/jem.20150894. Epub 2016 Jan 11. J Exp Med. 2016. PMID: 26755704 Free PMC article.
Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.
Katschke KJ Jr, Xi H, Cox C, Truong T, Malato Y, Lee WP, McKenzie B, Arceo R, Tao J, Rangell L, Reichelt M, Diehl L, Elstrott J, Weimer RM, van Lookeren Campagne M. Katschke KJ Jr, et al. Among authors: xi h. Sci Rep. 2018 Aug 24;8(1):13055. doi: 10.1038/s41598-018-30162-w. Sci Rep. 2018. PMID: 30143651 Free PMC article.
1,359 results