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Asymmetry in catalysis by Thermotoga maritima membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor.
Vidilaseris K, Kiriazis A, Turku A, Khattab A, Johansson NG, Leino TO, Kiuru PS, Boije Af Gennäs G, Meri S, Yli-Kauhaluoma J, Xhaard H, Goldman A. Vidilaseris K, et al. Among authors: xhaard h. Sci Adv. 2019 May 22;5(5):eaav7574. doi: 10.1126/sciadv.aav7574. eCollection 2019 May. Sci Adv. 2019. PMID: 31131322 Free PMC article.
[Pyrophosphate in medicine].
Goldman A, Boije af Gennis G, Xhaard H, Meri S, Yli-Kauhaluoma J. Goldman A, et al. Among authors: xhaard h. Duodecim. 2016;132(12):1111-7. Duodecim. 2016. PMID: 27483627 Review. Finnish.
Structural Isosteres of Phosphate Groups in the Protein Data Bank.
Zhang Y, Borrel A, Ghemtio L, Regad L, Boije Af Gennäs G, Camproux AC, Yli-Kauhaluoma J, Xhaard H. Zhang Y, et al. Among authors: xhaard h. J Chem Inf Model. 2017 Mar 27;57(3):499-516. doi: 10.1021/acs.jcim.6b00519. Epub 2017 Mar 13. J Chem Inf Model. 2017. PMID: 28234462
Stapled truncated orexin peptides as orexin receptor agonists.
Karhu L, Weisell J, Turunen PM, Leino TO, Pätsi H, Xhaard H, Kukkonen JP, Wallén EAA. Karhu L, et al. Among authors: xhaard h. Peptides. 2018 Apr;102:54-60. doi: 10.1016/j.peptides.2018.02.004. Epub 2018 Feb 21. Peptides. 2018. PMID: 29475074 Free article.
Adenosine analogs bearing phosphate isosteres as human MDO1 ligands.
Zhang Y, Jumppanen M, Maksimainen MM, Auno S, Awol Z, Ghemtio L, Venkannagari H, Lehtiö L, Yli-Kauhaluoma J, Xhaard H, Boije Af Gennäs G. Zhang Y, et al. Among authors: xhaard h. Bioorg Med Chem. 2018 May 1;26(8):1588-1597. doi: 10.1016/j.bmc.2018.02.006. Epub 2018 Feb 13. Bioorg Med Chem. 2018. PMID: 29501416
Azulene-based compounds for targeting orexin receptors.
Leino TO, Turku A, Yli-Kauhaluoma J, Kukkonen JP, Xhaard H, Wallén EAA. Leino TO, et al. Among authors: xhaard h. Eur J Med Chem. 2018 Sep 5;157:88-100. doi: 10.1016/j.ejmech.2018.07.040. Epub 2018 Jul 20. Eur J Med Chem. 2018. PMID: 30077889
58 results