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Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis.
Tsitsou-Kampeli A, Suzzi S, Kenigsbuch M, Satomi A, Strobelt R, Singer O, Feldmesser E, Purnapatre M, Colaiuta SP, David E, Cahalon L, Hahn O, Wyss-Coray T, Shaul Y, Amit I, Schwartz M. Tsitsou-Kampeli A, et al. Cell Rep Med. 2023 Nov 21;4(11):101278. doi: 10.1016/j.xcrm.2023.101278. Epub 2023 Nov 8. Cell Rep Med. 2023. PMID: 37944529 Free PMC article.
Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease.
Tsai AP, Dong C, Lin PB, Oblak AL, Viana Di Prisco G, Wang N, Hajicek N, Carr AJ, Lendy EK, Hahn O, Atkins M, Foltz AG, Patel J, Xu G, Moutinho M, Sondek J, Zhang Q, Mesecar AD, Liu Y, Atwood BK, Wyss-Coray T, Nho K, Bissel SJ, Lamb BT, Landreth GE. Tsai AP, et al. Immunity. 2023 Sep 12;56(9):2121-2136.e6. doi: 10.1016/j.immuni.2023.08.008. Epub 2023 Sep 1. Immunity. 2023. PMID: 37659412 Free article.
Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease.
Wang L, Nykänen NP, Western D, Gorijala P, Timsina J, Li F, Wang Z, Ali M, Yang C, Liu M, Brock W, Marquié M, Boada M, Alvarez I, Aguilar M, Pastor P, Ruiz A, Puerta R, Orellana A, Rutledge J, Oh H, Greicius MD, Le Guen Y, Perrin RJ, Wyss-Coray T, Jefferson A, Hohman TJ, Graff-Radford N, Mori H, Goate A, Levin J, Sung YJ, Cruchaga C. Wang L, et al. Among authors: wyss coray t. Mol Neurodegener. 2024 Jan 3;19(1):1. doi: 10.1186/s13024-023-00687-4. Mol Neurodegener. 2024. PMID: 38172904 Free PMC article.
CSF proteomic profiling with amyloid/tau positivity identifies distinctive sex-different alteration of multiple proteins involved in Alzheimer's disease.
Do AN, Ali M, Timsina J, Wang L, Western D, Liu M, Sanford J, Rosende-Roca M, Boada M, Puerta R, Wilson T, Ruiz A, Pastor P; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Wyss-Coray T, Cruchaga C, Sung YJ. Do AN, et al. Among authors: wyss coray t. medRxiv [Preprint]. 2024 Mar 16:2024.03.15.24304164. doi: 10.1101/2024.03.15.24304164. medRxiv. 2024. PMID: 38559166 Free PMC article. Preprint.
SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination.
Iram T, Garcia MA, Amand J, Kaur A, Atkins M, Iyer M, Lam M, Ambiel N, Jorgens DM, Keller A, Wyss-Coray T, Kern F, Zuchero JB. Iram T, et al. Among authors: wyss coray t. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2307250121. doi: 10.1073/pnas.2307250121. Epub 2024 Mar 14. Proc Natl Acad Sci U S A. 2024. PMID: 38483990
APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia.
Haney MS, Pálovics R, Munson CN, Long C, Johansson PK, Yip O, Dong W, Rawat E, West E, Schlachetzki JCM, Tsai A, Guldner IH, Lamichhane BS, Smith A, Schaum N, Calcuttawala K, Shin A, Wang YH, Wang C, Koutsodendris N, Serrano GE, Beach TG, Reiman EM, Glass CK, Abu-Remaileh M, Enejder A, Huang Y, Wyss-Coray T. Haney MS, et al. Among authors: wyss coray t. Nature. 2024 Apr;628(8006):154-161. doi: 10.1038/s41586-024-07185-7. Epub 2024 Mar 13. Nature. 2024. PMID: 38480892 Free PMC article.
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson's disease.
Rutledge J, Lehallier B, Zarifkar P, Losada PM, Shahid-Besanti M, Western D, Gorijala P, Ryman S, Yutsis M, Deutsch GK, Mormino E, Trelle A, Wagner AD, Kerchner GA, Tian L, Cruchaga C, Henderson VW, Montine TJ, Borghammer P, Wyss-Coray T, Poston KL. Rutledge J, et al. Among authors: wyss coray t. Acta Neuropathol. 2024 Mar 11;147(1):52. doi: 10.1007/s00401-024-02706-0. Acta Neuropathol. 2024. PMID: 38467937 Free PMC article.
259 results