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Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation.
Fabre T, Barron AMS, Christensen SM, Asano S, Bound K, Lech MP, Wadsworth MH 2nd, Chen X, Wang C, Wang J, McMahon J, Schlerman F, White A, Kravarik KM, Fisher AJ, Borthwick LA, Hart KM, Henderson NC, Wynn TA, Dower K. Fabre T, et al. Among authors: wynn ta. Sci Immunol. 2023 Apr 14;8(82):eadd8945. doi: 10.1126/sciimmunol.add8945. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027478
Cytokine mediated tissue fibrosis.
Borthwick LA, Wynn TA, Fisher AJ. Borthwick LA, et al. Among authors: wynn ta. Biochim Biophys Acta. 2013 Jul;1832(7):1049-60. doi: 10.1016/j.bbadis.2012.09.014. Epub 2012 Oct 6. Biochim Biophys Acta. 2013. PMID: 23046809 Free PMC article. Review.
Fibrosis: from mechanisms to medicines.
Henderson NC, Rieder F, Wynn TA. Henderson NC, et al. Among authors: wynn ta. Nature. 2020 Nov;587(7835):555-566. doi: 10.1038/s41586-020-2938-9. Epub 2020 Nov 25. Nature. 2020. PMID: 33239795 Free PMC article. Review.
Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis.
Vannella KM, Barron L, Borthwick LA, Kindrachuk KN, Narasimhan PB, Hart KM, Thompson RW, White S, Cheever AW, Ramalingam TR, Wynn TA. Vannella KM, et al. Among authors: wynn ta. PLoS Pathog. 2014 Sep 11;10(9):e1004372. doi: 10.1371/journal.ppat.1004372. eCollection 2014 Sep. PLoS Pathog. 2014. PMID: 25211233 Free PMC article.
Acidic chitinase primes the protective immune response to gastrointestinal nematodes.
Vannella KM, Ramalingam TR, Hart KM, de Queiroz Prado R, Sciurba J, Barron L, Borthwick LA, Smith AD, Mentink-Kane M, White S, Thompson RW, Cheever AW, Bock K, Moore I, Fitz LJ, Urban JF Jr, Wynn TA. Vannella KM, et al. Among authors: wynn ta. Nat Immunol. 2016 May;17(5):538-44. doi: 10.1038/ni.3417. Epub 2016 Apr 4. Nat Immunol. 2016. PMID: 27043413 Free PMC article.
243 results