Wuttke TV - Search Results

1

Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.

Auffenberg E, Hedrich UB, Barbieri R, Miely D, Groschup B, Wuttke TV, Vogel N, Lührs P, Zanardi I, Bertelli S, Spielmann N, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Pusch M, Dichgans M, Lerche H, Gavazzo P, Plesnila N, Freilinger T. Auffenberg E, et al. Among authors: wuttke tv. J Clin Invest. 2021 Nov 1;131(21):e142202. doi: 10.1172/JCI142202. J Clin Invest. 2021. PMID: 34546973 Free PMC article.

2

The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate.

Wuttke TV, Seebohm G, Bail S, Maljevic S, Lerche H. Wuttke TV, et al. Mol Pharmacol. 2005 Apr;67(4):1009-17. doi: 10.1124/mol.104.010793. Epub 2005 Jan 20. Mol Pharmacol. 2005. PMID: 15662042

3

Novel anticonvulsant drugs targeting voltage-dependent ion channels.

Wuttke TV, Lerche H. Wuttke TV, et al. Expert Opin Investig Drugs. 2006 Oct;15(10):1167-77. doi: 10.1517/13543784.15.10.1167. Expert Opin Investig Drugs. 2006. PMID: 16989594 Review.

4

Neutralization of a negative charge in the S1-S2 region of the KV7.2 (KCNQ2) channel affects voltage-dependent activation in neonatal epilepsy.

Wuttke TV, Penzien J, Fauler M, Seebohm G, Lehmann-Horn F, Lerche H, Jurkat-Rott K. Wuttke TV, et al. J Physiol. 2008 Jan 15;586(2):545-55. doi: 10.1113/jphysiol.2007.143826. Epub 2007 Nov 15. J Physiol. 2008. PMID: 18006581 Free PMC article.

5

Nervous system KV7 disorders: breakdown of a subthreshold brake.

Maljevic S, Wuttke TV, Lerche H. Maljevic S, et al. Among authors: wuttke tv. J Physiol. 2008 Apr 1;586(7):1791-801. doi: 10.1113/jphysiol.2008.150656. Epub 2008 Jan 31. J Physiol. 2008. PMID: 18238816 Free PMC article. Review.

6

KV7 channelopathies.

Maljevic S, Wuttke TV, Seebohm G, Lerche H. Maljevic S, et al. Among authors: wuttke tv. Pflugers Arch. 2010 Jul;460(2):277-88. doi: 10.1007/s00424-010-0831-3. Epub 2010 Apr 18. Pflugers Arch. 2010. PMID: 20401729 Review.

7

Retigabine/Ezogabine, a KCNQ/K(V)7 channel opener: pharmacological and clinical data.

Orhan G, Wuttke TV, Nies AT, Schwab M, Lerche H. Orhan G, et al. Among authors: wuttke tv. Expert Opin Pharmacother. 2012 Aug;13(12):1807-16. doi: 10.1517/14656566.2012.706278. Epub 2012 Jul 12. Expert Opin Pharmacother. 2012. PMID: 22783830 Review.

8

Human Cerebrospinal fluid promotes long-term neuronal viability and network function in human neocortical organotypic brain slice cultures.

Schwarz N, Hedrich UBS, Schwarz H, P A H, Dammeier N, Auffenberg E, Bedogni F, Honegger JB, Lerche H, Wuttke TV, Koch H. Schwarz N, et al. Among authors: wuttke tv. Sci Rep. 2017 Sep 25;7(1):12249. doi: 10.1038/s41598-017-12527-9. Sci Rep. 2017. PMID: 28947761 Free PMC article.

9

Long-term adult human brain slice cultures as a model system to study human CNS circuitry and disease.

Schwarz N, Uysal B, Welzer M, Bahr JC, Layer N, Löffler H, Stanaitis K, Pa H, Weber YG, Hedrich UB, Honegger JB, Skodras A, Becker AJ, Wuttke TV, Koch H. Schwarz N, et al. Among authors: wuttke tv. Elife. 2019 Sep 9;8:e48417. doi: 10.7554/eLife.48417. Elife. 2019. PMID: 31498083 Free PMC article.

10

The effect of lamotrigine and other antiepileptic drugs on respiratory rhythm generation in the pre-Bötzinger complex.

Layer N, Brandes J, Lührs PJ, Wuttke TV, Koch H. Layer N, et al. Among authors: wuttke tv. Epilepsia. 2021 Nov;62(11):2790-2803. doi: 10.1111/epi.17066. Epub 2021 Sep 23. Epilepsia. 2021. PMID: 34553376

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