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A microbial supply chain for production of the anti-cancer drug vinblastine.
Zhang J, Hansen LG, Gudich O, Viehrig K, Lassen LMM, Schrübbers L, Adhikari KB, Rubaszka P, Carrasquer-Alvarez E, Chen L, D'Ambrosio V, Lehka B, Haidar AK, Nallapareddy S, Giannakou K, Laloux M, Arsovska D, Jørgensen MAK, Chan LJG, Kristensen M, Christensen HB, Sudarsan S, Stander EA, Baidoo E, Petzold CJ, Wulff T, O'Connor SE, Courdavault V, Jensen MK, Keasling JD. Zhang J, et al. Among authors: wulff t. Nature. 2022 Sep;609(7926):341-347. doi: 10.1038/s41586-022-05157-3. Epub 2022 Aug 31. Nature. 2022. PMID: 36045295 Free PMC article.
Multiplex secretome engineering enhances recombinant protein production and purity.
Kol S, Ley D, Wulff T, Decker M, Arnsdorf J, Schoffelen S, Hansen AH, Jensen TL, Gutierrez JM, Chiang AWT, Masson HO, Palsson BO, Voldborg BG, Pedersen LE, Kildegaard HF, Lee GM, Lewis NE. Kol S, et al. Among authors: wulff t. Nat Commun. 2020 Apr 20;11(1):1908. doi: 10.1038/s41467-020-15866-w. Nat Commun. 2020. PMID: 32313013 Free PMC article.
DisCoTune: versatile auxiliary plasmids for the production of disulphide-containing proteins and peptides in the E. coli T7 system.
Bertelsen AB, Hackney CM, Bayer CN, Kjelgaard LD, Rennig M, Christensen B, Sørensen ES, Safavi-Hemami H, Wulff T, Ellgaard L, Nørholm MHH. Bertelsen AB, et al. Among authors: wulff t. Microb Biotechnol. 2021 Nov;14(6):2566-2580. doi: 10.1111/1751-7915.13895. Epub 2021 Aug 18. Microb Biotechnol. 2021. PMID: 34405535 Free PMC article.
An automated workflow for multi-omics screening of microbial model organisms.
Donati S, Mattanovich M, Hjort P, Jacobsen SAB, Blomquist SD, Mangaard D, Gurdo N, Pastor FP, Maury J, Hanke R, Herrgård MJ, Wulff T, Jakočiūnas T, Nielsen LK, McCloskey D. Donati S, et al. Among authors: wulff t. NPJ Syst Biol Appl. 2023 May 19;9(1):14. doi: 10.1038/s41540-023-00277-6. NPJ Syst Biol Appl. 2023. PMID: 37208327 Free PMC article.
62 results