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Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes.
Kim A, Knudsen JG, Madara JC, Benrick A, Hill TG, Abdul Kadir L, Kellard JA, Mellander L, Miranda C, Lin H, James T, Suba K, Spigelman AF, Wu Y, MacDonald PE, Wernstedt Asterholm I, Magnussen T, Christensen M, Vilsbøll T, Salem V, Knop FK, Rorsman P, Lowell BB, Briant LJ. Kim A, et al. Among authors: wu y. Elife. 2021 Nov 17;10:e72919. doi: 10.7554/eLife.72919. Elife. 2021. PMID: 34787082 Free PMC article.
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.
Vergari E, Knudsen JG, Ramracheya R, Salehi A, Zhang Q, Adam J, Asterholm IW, Benrick A, Briant LJB, Chibalina MV, Gribble FM, Hamilton A, Hastoy B, Reimann F, Rorsman NJG, Spiliotis II, Tarasov A, Wu Y, Ashcroft FM, Rorsman P. Vergari E, et al. Among authors: wu y. Nat Commun. 2019 Jan 11;10(1):139. doi: 10.1038/s41467-018-08193-8. Nat Commun. 2019. PMID: 30635569 Free PMC article.
Adipocyte-specific ablation of the Ca2+ pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue.
Bauzá-Thorbrügge M, Banke E, Chanclón B, Peris E, Wu Y, Musovic S, Jönsson C, Strålfors P, Rorsman P, Olofsson CS, Wernstedt Asterholm I. Bauzá-Thorbrügge M, et al. Among authors: wu y. Mol Metab. 2022 Sep;63:101535. doi: 10.1016/j.molmet.2022.101535. Epub 2022 Jun 24. Mol Metab. 2022. PMID: 35760318 Free PMC article.
VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics.
Davegårdh C, Säll J, Benrick A, Broholm C, Volkov P, Perfilyev A, Henriksen TI, Wu Y, Hjort L, Brøns C, Hansson O, Pedersen M, Würthner JU, Pfeffer K, Nilsson E, Vaag A, Stener-Victorin E, Pircs K, Scheele C, Ling C. Davegårdh C, et al. Among authors: wu y. Nat Commun. 2021 Apr 23;12(1):2431. doi: 10.1038/s41467-021-22068-5. Nat Commun. 2021. PMID: 33893273 Free PMC article.
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