Wu Y - Search Results

1

Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-G_i Complex Structures.

Hua T, Li X, Wu L, Iliopoulos-Tsoutsouvas C, Wang Y, Wu M, Shen L, Brust CA, Nikas SP, Song F, Song X, Yuan S, Sun Q, Wu Y, Jiang S, Grim TW, Benchama O, Stahl EL, Zvonok N, Zhao S, Bohn LM, Makriyannis A, Liu ZJ. Hua T, et al. Among authors: wu y, wu m, wu l. Cell. 2020 Feb 20;180(4):655-665.e18. doi: 10.1016/j.cell.2020.01.008. Epub 2020 Jan 30. Cell. 2020. PMID: 32004463 Free PMC article.

2

Crystal Structure of the Human Cannabinoid Receptor CB₁.

Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, Kufareva I, Wu B, Zhao Q, Hanson MA, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ. Hua T, et al. Among authors: wu y, wu b. Cell. 2016 Oct 20;167(3):750-762.e14. doi: 10.1016/j.cell.2016.10.004. Cell. 2016. PMID: 27768894 Free PMC article.

3

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.

Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, Hanson MA, Cherezov V, Stevens RC, Tan W, Tao H, Xu F. Zhang X, et al. Among authors: wu y. Nat Commun. 2017 May 17;8:15383. doi: 10.1038/ncomms15383. Nat Commun. 2017. PMID: 28513578 Free PMC article.

4

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.

Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, Han GW, Lau J, Wu B, Hanson MA, Liu ZJ, Wang MW, Stevens RC. Song G, et al. Among authors: wu y, wu f, wu b. Nature. 2017 Jun 8;546(7657):312-315. doi: 10.1038/nature22378. Epub 2017 May 17. Nature. 2017. PMID: 28514449

5

Crystal structures of agonist-bound human cannabinoid receptor CB₁.

Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, Zhao S, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ. Hua T, et al. Among authors: wu y. Nature. 2017 Jul 27;547(7664):468-471. doi: 10.1038/nature23272. Epub 2017 Jul 5. Nature. 2017. PMID: 28678776 Free PMC article.

6

Structural insights into the committed step of bacterial phospholipid biosynthesis.

Li Z, Tang Y, Wu Y, Zhao S, Bao J, Luo Y, Li D. Li Z, et al. Among authors: wu y. Nat Commun. 2017 Nov 22;8(1):1691. doi: 10.1038/s41467-017-01821-9. Nat Commun. 2017. PMID: 29167463 Free PMC article.

7

5-HT_2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, Wacker D, Han GW, Cheng J, Katritch V, Jensen AA, Hanson MA, Zhao S, Gloriam DE, Roth BL, Stevens RC, Liu ZJ. Peng Y, et al. Among authors: wu y. Cell. 2018 Feb 8;172(4):719-730.e14. doi: 10.1016/j.cell.2018.01.001. Epub 2018 Feb 1. Cell. 2018. PMID: 29398112 Free PMC article.

8

Identification of natural products as novel ligands for the human 5-HT_2C receptor.

Peng Y, Zhao S, Wu Y, Cao H, Xu Y, Liu X, Shui W, Cheng J, Zhao S, Shen L, Ma J, Quinn RJ, Stevens RC, Zhong G, Liu ZJ. Peng Y, et al. Among authors: wu y. Biophys Rep. 2018;4(1):50-61. doi: 10.1007/s41048-018-0047-1. Epub 2018 Mar 9. Biophys Rep. 2018. PMID: 29577069 Free PMC article.

9

High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening.

Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, Hanson MA, Liu ZJ, Wang MW, Stevens RC, Shui W. Qin S, et al. Among authors: wu y. Chem Sci. 2018 Feb 20;9(12):3192-3199. doi: 10.1039/c7sc04698g. eCollection 2018 Mar 28. Chem Sci. 2018. PMID: 29732102 Free PMC article.

10

Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y₁ and P2Y₁₂ receptors.

Liu X, Gao ZG, Wu Y, Stevens RC, Jacobson KA, Zhao S. Liu X, et al. Among authors: wu y. Sci Rep. 2018 May 24;8(1):8084. doi: 10.1038/s41598-018-26577-0. Sci Rep. 2018. PMID: 29795391 Free PMC article.

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