Wu X - Search Results

1

POLD1 DEDD Motif Mutation Confers Hypermutation in Endometrial Cancer and Durable Response to Pembrolizumab.

Wei CH, Wang EW, Ma L, Zhou Y, Zheng L, Hampel H, Shehayeb S, Lee S, Cohen J, Kohut A, Fan F, Rosen S, Wu X, Shen B, Zhao Y. Wei CH, et al. Among authors: wu x. Cancers (Basel). 2023 Nov 30;15(23):5674. doi: 10.3390/cancers15235674. Cancers (Basel). 2023. PMID: 38067377 Free PMC article.

2

Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer.

Zheng L, Dai H, Hegde ML, Zhou M, Guo Z, Wu X, Wu J, Su L, Zhong X, Mitra S, Huang Q, Kernstine KH, Pfeifer GP, Shen B. Zheng L, et al. Among authors: wu x, wu j. Cell Res. 2011 Jul;21(7):1052-67. doi: 10.1038/cr.2011.35. Epub 2011 Mar 8. Cell Res. 2011. PMID: 21383776 Free PMC article.

3

Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression.

Zheng L, Dai H, Zhou M, Li X, Liu C, Guo Z, Wu X, Wu J, Wang C, Zhong J, Huang Q, Garcia-Aguilar J, Pfeifer GP, Shen B. Zheng L, et al. Among authors: wu x, wu j. Nat Commun. 2012 May 8;3:815. doi: 10.1038/ncomms1825. Nat Commun. 2012. PMID: 22569363 Free PMC article.

4

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

Zhou L, Dai H, Wu J, Zhou M, Yuan H, Du J, Yang L, Wu X, Xu H, Hua Y, Xu J, Zheng L, Shen B. Zhou L, et al. Among authors: wu x, wu j. FASEB J. 2017 Jan;31(1):132-147. doi: 10.1096/fj.201600631R. Epub 2016 Sep 30. FASEB J. 2017. PMID: 27694478 Free PMC article.

Altogether, our results reveal an important role of FEN1 phosphorylation to counteract oxygen-induced stress in the heart during the fetal-to-neonatal transition.-Zhou, L., Dai, H., Wu, J., Zhou, M., Yuan, H., Du, J., Yang, L., Wu, X., Xu, H., Hua, Y., Xu, J. …

Altogether, our results reveal an important role of FEN1 phosphorylation to counteract oxygen-induced stress in the heart during the fetal-t …

5

JMJD1B Demethylates H4R3me2s and H3K9me2 to Facilitate Gene Expression for Development of Hematopoietic Stem and Progenitor Cells.

Li S, Ali S, Duan X, Liu S, Du J, Liu C, Dai H, Zhou M, Zhou L, Yang L, Chu P, Li L, Bhatia R, Schones DE, Wu X, Xu H, Hua Y, Guo Z, Yang Y, Zheng L, Shen B. Li S, et al. Among authors: wu x. Cell Rep. 2018 Apr 10;23(2):389-403. doi: 10.1016/j.celrep.2018.03.051. Cell Rep. 2018. PMID: 29641999 Free PMC article.

6

hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability.

Li Z, Liu B, Jin W, Wu X, Zhou M, Liu VZ, Goel A, Shen Z, Zheng L, Shen B. Li Z, et al. Among authors: wu x. EMBO J. 2018 Jul 13;37(14):e96729. doi: 10.15252/embj.201796729. Epub 2018 May 17. EMBO J. 2018. PMID: 29773570 Free PMC article.

7

Leflunomide Synergizes with Gemcitabine in Growth Inhibition of PC Cells and Impairs c-Myc Signaling through PIM Kinase Targeting.

Buettner R, Morales C, Wu X, Sanchez JF, Li H, Melstrom LG, Rosen ST. Buettner R, et al. Among authors: wu x. Mol Ther Oncolytics. 2019 May 17;14:149-158. doi: 10.1016/j.omto.2019.04.006. eCollection 2019 Sep 27. Mol Ther Oncolytics. 2019. PMID: 31211245 Free PMC article.

8

Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma.

Chen R, Herrera AF, Hou J, Chen L, Wu J, Guo Y, Synold TW, Ngo VN, Puverel S, Mei M, Popplewell L, Yi S, Song JY, Tao S, Wu X, Chan WC, Forman SJ, Kwak LW, Rosen ST, Newman EM. Chen R, et al. Among authors: wu x, wu j. Clin Cancer Res. 2020 Mar 1;26(5):1034-1044. doi: 10.1158/1078-0432.CCR-19-1768. Epub 2019 Dec 6. Clin Cancer Res. 2020. PMID: 31811017 Free PMC article. Clinical Trial.

9

Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine.

Buettner R, Nguyen LXT, Morales C, Chen MH, Wu X, Chen LS, Hoang DH, Hernandez Vargas S, Pullarkat V, Gandhi V, Marcucci G, Rosen ST. Buettner R, et al. Among authors: wu x. J Hematol Oncol. 2021 Apr 26;14(1):70. doi: 10.1186/s13045-021-01076-4. J Hematol Oncol. 2021. PMID: 33902674 Free PMC article.

10

Targeting the non-ATP-binding pocket of the MAP kinase p38γ mediates a novel mechanism of cytotoxicity in cutaneous T-cell lymphoma (CTCL).

Zhang XH, Chen CH, Li H, Hsiang J, Wu X, Hu W, Horne D, Nam S, Shively J, Rosen ST. Zhang XH, et al. Among authors: wu x. FEBS Lett. 2021 Oct;595(20):2570-2592. doi: 10.1002/1873-3468.14186. Epub 2021 Sep 15. FEBS Lett. 2021. PMID: 34455585 Free PMC article.

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