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Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma.
Shenoy N, Bhagat TD, Cheville J, Lohse C, Bhattacharyya S, Tischer A, Machha V, Gordon-Mitchell S, Choudhary G, Wong LF, Gross L, Ressigue E, Leibovich B, Boorjian SA, Steidl U, Wu X, Pradhan K, Gartrell B, Agarwal B, Pagliaro L, Suzuki M, Greally JM, Rakheja D, Thompson RH, Susztak K, Witzig T, Zou Y, Verma A. Shenoy N, et al. Among authors: wu x. J Clin Invest. 2019 Mar 4;129(4):1612-1625. doi: 10.1172/JCI98747. eCollection 2019 Mar 4. J Clin Invest. 2019. PMID: 30702441 Free PMC article.
Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance.
Mraz M, Zent CS, Church AK, Jelinek DF, Wu X, Pospisilova S, Ansell SM, Novak AJ, Kay NE, Witzig TE, Nowakowski GS. Mraz M, et al. Among authors: wu x. Br J Haematol. 2011 Oct;155(1):53-64. doi: 10.1111/j.1365-2141.2011.08794.x. Epub 2011 Jul 12. Br J Haematol. 2011. PMID: 21749361 Free PMC article.
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.
Correia C, Schneider PA, Dai H, Dogan A, Maurer MJ, Church AK, Novak AJ, Feldman AL, Wu X, Ding H, Meng XW, Cerhan JR, Slager SL, Macon WR, Habermann TM, Karp JE, Gore SD, Kay NE, Jelinek DF, Witzig TE, Nowakowski GS, Kaufmann SH. Correia C, et al. Among authors: wu x. Blood. 2015 Jan 22;125(4):658-67. doi: 10.1182/blood-2014-04-571786. Epub 2014 Dec 1. Blood. 2015. PMID: 25452615 Free PMC article. Clinical Trial.
The effect of CRM1 inhibition on human non-Hodgkin lymphoma cells.
Abeykoon JP, Paludo J, Nowakowski KE, Stenson MJ, King RL, Wellik LE, Wu X, Witzig TE. Abeykoon JP, et al. Among authors: wu x. Blood Cancer J. 2019 Feb 26;9(3):24. doi: 10.1038/s41408-019-0188-6. Blood Cancer J. 2019. PMID: 30808874 Free PMC article. No abstract available.
A new tool in the cancer immunotherapy toolbox?
Wu X, Witzig TE. Wu X, et al. Ann Lymphoma. 2018 Mar;2(3):2. doi: 10.21037/aol.2018.03.01. Epub 2018 Mar 20. Ann Lymphoma. 2018. PMID: 34263259 Free PMC article. No abstract available.
Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL.
Ding W, LaPlant BR, Call TG, Parikh SA, Leis JF, He R, Shanafelt TD, Sinha S, Le-Rademacher J, Feldman AL, Habermann TM, Witzig TE, Wiseman GA, Lin Y, Asmus E, Nowakowski GS, Conte MJ, Bowen DA, Aitken CN, Van Dyke DL, Greipp PT, Liu X, Wu X, Zhang H, Secreto CR, Tian S, Braggio E, Wellik LE, Micallef I, Viswanatha DS, Yan H, Chanan-Khan AA, Kay NE, Dong H, Ansell SM. Ding W, et al. Among authors: wu x. Blood. 2017 Jun 29;129(26):3419-3427. doi: 10.1182/blood-2017-02-765685. Epub 2017 Apr 19. Blood. 2017. PMID: 28424162 Free PMC article. Clinical Trial.
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