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Multiplex genome engineering using CRISPR/Cas systems.
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Cong L, et al. Among authors: wu x. Science. 2013 Feb 15;339(6121):819-23. doi: 10.1126/science.1231143. Epub 2013 Jan 3. Science. 2013. PMID: 23287718 Free PMC article.
DNA targeting specificity of RNA-guided Cas9 nucleases.
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. Hsu PD, et al. Among authors: wu x. Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873081 Free PMC article.
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Wu X, et al. Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752079 Free PMC article.
Editing DNA Methylation in the Mammalian Genome.
Liu XS, Wu H, Ji X, Stelzer Y, Wu X, Czauderna S, Shu J, Dadon D, Young RA, Jaenisch R. Liu XS, et al. Among authors: wu h, wu x. Cell. 2016 Sep 22;167(1):233-247.e17. doi: 10.1016/j.cell.2016.08.056. Cell. 2016. PMID: 27662091 Free PMC article.
Collateral activity of the CRISPR/RfxCas13d system in human cells.
Shi P, Murphy MR, Aparicio AO, Kesner JS, Fang Z, Chen Z, Trehan A, Guo Y, Wu X. Shi P, et al. Among authors: wu x. Commun Biol. 2023 Mar 28;6(1):334. doi: 10.1038/s42003-023-04708-2. Commun Biol. 2023. PMID: 36977923 Free PMC article.
Target specificity of the CRISPR-Cas9 system.
Wu X, Kriz AJ, Sharp PA. Wu X, et al. Quant Biol. 2014 Jun;2(2):59-70. doi: 10.1007/s40484-014-0030-x. Quant Biol. 2014. PMID: 25722925 Free PMC article.
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