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Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.
Wang T, Gross C, Desai AA, Zemskov E, Wu X, Garcia AN, Jacobson JR, Yuan JX, Garcia JG, Black SM. Wang T, et al. Among authors: wu x. Am J Physiol Lung Cell Mol Physiol. 2017 Apr 1;312(4):L452-L476. doi: 10.1152/ajplung.00231.2016. Epub 2016 Dec 15. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27979857 Free PMC article. Review.
Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics.
Lu Q, Zemskov EA, Sun X, Wang H, Yegambaram M, Wu X, Garcia-Flores A, Song S, Tang H, Kangath A, Cabanillas GZ, Yuan JX, Wang T, Fineman JR, Black SM. Lu Q, et al. Among authors: wu x. Redox Biol. 2021 Jan;38:101785. doi: 10.1016/j.redox.2020.101785. Epub 2020 Nov 12. Redox Biol. 2021. PMID: 33221570 Free PMC article.
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.
Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX. Wang Z, et al. Among authors: wu x, wu l. Am J Physiol Cell Physiol. 2021 Dec 1;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20. Am J Physiol Cell Physiol. 2021. PMID: 34669509 Free PMC article.
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