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Intramuscular delivery of adenovirus serotype 5 vector expressing humanized protective antigen induces rapid protection against anthrax that may bypass intranasally originated preexisting adenovirus immunity.
Wu S, Zhang Z, Yu R, Zhang J, Liu Y, Song X, Yi S, Liu J, Chen J, Yin Y, Xu J, Hou L, Chen W. Wu S, et al. Clin Vaccine Immunol. 2014 Feb;21(2):156-64. doi: 10.1128/CVI.00560-13. Epub 2013 Dec 4. Clin Vaccine Immunol. 2014. PMID: 24307239 Free PMC article.
Open-label phase I clinical trial of Ad5-EBOV in Africans in China.
Wu L, Zhang Z, Gao H, Li Y, Hou L, Yao H, Wu S, Liu J, Wang L, Zhai Y, Ou H, Lin M, Wu X, Liu J, Lang G, Xin Q, Wu G, Luo L, Liu P, Shentu J, Wu N, Sheng J, Qiu Y, Chen W, Li L. Wu L, et al. Among authors: wu x, wu g, wu s, wu n. Hum Vaccin Immunother. 2017 Sep 2;13(9):2078-2085. doi: 10.1080/21645515.2017.1342021. Epub 2017 Jul 14. Hum Vaccin Immunother. 2017. PMID: 28708962 Free PMC article. Clinical Trial.
Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models.
Guo Q, Chan JF, Poon VK, Wu S, Chan CC, Hou L, Yip CC, Ren C, Cai JP, Zhao M, Zhang AJ, Song X, Chan KH, Wang B, Kok KH, Wen Y, Yuen KY, Chen W. Guo Q, et al. Among authors: wu s. J Infect Dis. 2018 Jul 2;218(3):365-377. doi: 10.1093/infdis/jiy187. J Infect Dis. 2018. PMID: 29617816
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